Table 3

Definitions of inactive disease and clinical remission in childhood-onset systemic lupus erythematosus

Medication usage


Construct

Minimal time interval

Corticosteroids

Immunosuppressives

Preventive medicationsa

Medications to treat damage


Inactive diseaseb

Yes

Permissible

Permissible

Permissible

Permissible

Clinical remission on medication

6 months

Permissible

Permissible

Permissible

Permissible

Clinical remission on preventive medication

6 months

No

No

Permissible

Permissible

Clinical remission off medication

12 months

No

No

No

Permissible


aPreventive medications include systemic medications that can be used to prevent disease damage, such as statins, aspirin, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, bisphosphonates, vitamin D, and omega-3 fatty acids. bMedication exposure is not considered.

Mina and Brunner Arthritis Research & Therapy 2013 15:218   doi:10.1186/ar4256