Table 1

Epidemiologic, laboratory and capillaroscopic features of the two early systemic sclerosis series

Feature

Rheumatology Unit (n = 45)

Angiology Unit (n = 26)

P value


Sex (female/male ratio)

43/2

22/4

NS

Age (years)

41 (17-73)

37.5 (16-71)

NS

RP duration (years)

3 (0.5-24)

3 (1-20)

NS

Subset 1: antibody-positive, NVC-positive

26 (57.8)

6 (2.2)

0.0098

Anti-Scl-70 antibody-positive

5 (19.2)

0

ACA-positive

19 (73.1)

3 (50)

Anti-RNA polymerase III antibody-positive

2 (7.7)

3 (50)

Megacapillaries only

21 (80.8)

3 (50)

Avascular areas ± megacapillaries

5 (19.2)

3 (50)

Subset 2: antibody-positive, NVC-negative

16 (35.6)

0

-

AntiScl-70 antibody-positive

4 (25)

0

ACA-positive

12 (75)

0

Anti-RNA polymerase III antibody-positive

0

0

Subset 3: antibody-negative, NVC-positive

3 (6.7)

20 (76.9)

0.0001

Megacapillaries only

3 (100)

20 (100)

-

Avascular areas ± megacapillaries

0

0

-


All data expressed as median (range) or number (percentage). ACA, anticentromere antibody; NVC, nailfold videocapillaroscopy; RP, Raynaud's phenomenon.

Valentini et al. Arthritis Research & Therapy 2013 15:R63   doi:10.1186/ar4236

Open Data