Open Access Highly Accessed Research article

Early systemic sclerosis: marker autoantibodies and videocapillaroscopy patterns are each associated with distinct clinical, functional and cellular activation markers

Gabriele Valentini1*, Antonella Marcoccia2, Giovanna Cuomo1, Serena Vettori1, Michele Iudici1, Francesco Bondanini3, Carlo Santoriello4, Aldo Ciani5, Domenico Cozzolino6, Giovanni Maria De Matteis7, Salvatore Cappabianca8, Filiberto Vitelli9 and Alberto Spanò3

Author Affiliations

1 Rheumatology Unit, Second University of Naples, via Pansini 5, 80131 Naples, Italy

2 Angiology Unit, Sandro Pertini Hospital, via dei Monti Tiburtini 385, 00157 Rome, Italy

3 Clinical Biochemistry Service, Sandro Pertini Hospital, via dei Monti Tiburtini 385, 00157 Rome, Italy

4 Respiratory Physiopathology Unit, ASL-SA1, via Santoriello 2, Cava dei Tirreni (SA), Italy

5 Pneumology Unit, Sandro Pertini Hospital, via dei Monti Tiburtini 385, 00157 Rome, Italy

6 Internal Medicine Unit, Second University of Naples, via Pansini 5, 80131 Naples, Italy

7 Cardiology Unit, Sandro Pertini Hospital, via dei Monti Tiburtini 385, 00157 Rome, Italy

8 Radiology, Radiotherapy and Nuclear Medicine Unit, Second University of Naples, Piazza Miraglia 5, 80131 Naples, Italy

9 Radiology Unit, Sandro Pertini Hospital, via dei Monti Tiburtini 385, 00157 Rome, Italy

For all author emails, please log on.

Arthritis Research & Therapy 2013, 15:R63  doi:10.1186/ar4236

Published: 29 May 2013

Additional files

Additional file 1:

Table S1 presenting epidemiologic, laboratory and capillaroscopic features in patients who did not meet EULAR/ACR classification criteria, and figure legends for Figures S1, S2, and S3.

Format: DOCX Size: 16KB Download file

Open Data

Additional file 2:

Figure S1 showing the prevalence of puffy fingers, arthritis and NVC scleroderma pattern in patients who did not meet EULAR/ACR classification criteria.

Format: PPT Size: 275KB Download file

This file can be viewed with: Microsoft PowerPoint Viewer

Open Data

Additional file 3:

Figure S2 showing the prevalence of DCLO impairment and autoantibody positivity in patients who did not meet EULAR/ACR classification criteria.

Format: PPT Size: 135KB Download file

This file can be viewed with: Microsoft PowerPoint Viewer

Open Data

Additional file 4:

Figure S3 showing serum levels of ICTP, sE-selectin, sIL2Rαa and sE-selectin in patients who did not meet EULAR/ACR classification criteria.

Format: PPT Size: 435KB Download file

This file can be viewed with: Microsoft PowerPoint Viewer

Open Data