Table 2

Nailfold videocapillaroscopy patterns and endothelial marker levels in peripheral blood or serum of patients with systemic sclerosis included in the discovery cohort

Capillaroscopy pattern

P value


Early

Median (range)

Active

Median (range)

Late

Median (range)


EPCs (106 Lin-mononuclear cells)

61 (29-573)

82 (21-300)

31 (5-300)

< 0.0001

CECs (106 Lin-mononuclear cells)

81 (10-342)

36 (5-155)

77 (6-472)

0.4

VEGF (pg/ml)

518 (161-1,028)

493 (156-1,146)

814 (189-1,564)

0.01

PlGF (pg/ml)

9.6 (4.6-24.2)

9.9 (0.7-19.6)

10.5 (2.3-26.5)

0.8

sVCAM-1 (ng/ml)

766 (482-1,828)

694 (354-1,405)

767 (459-1,314)

0.4

Tie-2 (ng/ml)

24.4 (12.9-29.4)

21.1 (14.1-27.1)

22.2 (16-39.6)

0.3

Endostatin (ng/ml)

185 (88-477)

139 (54-178)

150 (22-662)

0.3

Endoglin (CD105) (ng/ml)

3.7 (1.9-5.0)

3.9 (2.8-5.6)

3.5 (2.6-5.1)

0.5

Endothelin-1 (pg/ml)

1.5 (1.0-3.6)

2.5 (0.9-7.2)

1.7 (0.4-3.1)

0.02

Angiopoietin-2 (pg/ml)

2,166 (1241-3,312)

2,016 (1,249-4,027)

2202 (1,512-5,148)

0.5

von Willebrand factor antigen (%)

180 (95-266)

169 (69-304)

170 (83-302)

0.9


Avouac et al. Arthritis Research & Therapy 2013 15:R55   doi:10.1186/ar4217

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