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Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: pharmacokinetics and correlation with digital perfusion

Ami A Shah*, Elena Schiopu, Laura K Hummers, Michael Wade, Kristine Phillips, Cynthia Anderson, Robert Wise, Francesco Boin, James R Seibold, Fredrick Wigley and Kristan D Rollins

Arthritis Research & Therapy 2013, 15:R54  doi:10.1186/ar4216


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