Anti-Rpp25 antibodies in Th/To immunoprecipitation (IP)-positive and IP-negative samples measured by enzyme-linked immunosorbent assay (ELISA). Comparative descriptive analysis is shown in a). In b) the receiver operating characteristic (ROC) analysis shows good discrimination between anti-Th/To IP-positive patients (n = 14) and controls (anti-Th/To-negative SSc and healthy individuals, n = 156). AUC, area under the curve.
Mahler et al. Arthritis Research & Therapy 2013 15:R50 doi:10.1186/ar4210