Table 2

Prevalence of myositis-specific/related autoantibodies in adult-onset DM

Adult-onset DM

Mexico City

Adult-onset DM

Guadalajara


Number

44

17

Age (mean ± SD)

46.7 ± 14.1a

39.9 ± 12.1a

Male

32%

18%

Autoantibodies

Jo-1

4%

0%

Mi-2

(95% CI)

59%b

(43.3 to 73.7)

12%b

(1.5 to 36.4)

p155/140

(95% CI)

9%c

(2.5 to 21.7)

35%c

(14.2 to 61.7)

MJ/NXP-2

4%

6%

SAE

4%

0%

SRP

0%

6%

PM-Scl

2%

12%

U1RNP

2%

0%

Negative

16%

29%

Su/Ago2

14%

0%

Ro60

11%

24%

Ro52d

21%

29%


aP = 0.035 by Mann-Whitney; bP = 0.0012; cP = 0.02, by Fisher exact test; dsome samples were not tested due to availability. All were determined by immunoprecipitation except anti-Ro52 determined by ELISA. Anti-EJ, PL-7, PL-12, OJ were not found. DM, dermatomyositis; negative, negative for myositis-specifc/related autoantibodies, anti-Jo-1 to -U1RNP in the table; PM, polymyositis; SAE, small ubiquitin-like modifier activating enzyme; SRP, signal recognition particle.

Petri et al. Arthritis Research & Therapy 2013 15:R48   doi:10.1186/ar4207

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