Table 1

Prevalence of autoantibodies in Mexican patients with PM/DM

PM/DM

PM

DM

Adult-onset DM

Juvenile- onset DM


Number

95

29

66

61

5

Age

44.4

48.4

42.8

45.3

18.2

Mean ± SD

± 14.2

± 10.2

± 15.3

± 14.4

± 9.7

Male

33%

41%

29%

28%

40%

Autoantibodies

Jo-1

4%

7%

3%

3%

0%

Mi-2

(95% CI)

35%

10%a

(2.1 to 26.5)

45%a

(33.1 to 58.2)

45%

40%

p155/140

(95% CI)

11%

0%b

(0.0 to 11.9)

15%b

(7.5 to 26.1)

16%

0%

MJ/NXP-2

3%

0%

5%

3%

20%

SAE

2%

0%

3%

3%

0%

SRP

3%

7%

2%

2%

0%

PM-Scl

3%

0%

5%

5%

0%

U1RNP

3%

7%

2%

2%

0%

Negative

36%

69%c

21%c

20%

40%

Su/Ago2

8%

7%

9%

10%

0%

Ro60

13%

7%

15%

15%

20%

Ro52d

21%

16%

22%

24%

0%


aP < 0.0001; bP < 0.05; cP < 0.0001 by Fisher exact test; dsome samples were not tested due to availability. All were determined by immunoprecipitation except anti-Ro52 determined by ELISA. Anti-EJ, PL-7, PL-12, OJ were not found. DM, dermatomyositis; negative, negative for myositis-specifc/related autoantibodies, anti-Jo-1 to -U1RNP in the table; PM, polymyositis; SAE, small ubiquitin-like modifier activating enzyme; SRP, signal recognition particle.

Petri et al. Arthritis Research & Therapy 2013 15:R48   doi:10.1186/ar4207

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