Table 2

Exercise tolerance and cardiorespiratory measurements before and after the exercise training

Variable

C-SLE trained

(n = 10)

C-SLE non-trained

(n = 9)

Control

(n = 10)


Time-to-exhaustion, minutes

PRE

10.1 (2.2)a

9.7 (1.6)a

13.7 (2.7)b

POST

12.8 (2.4)b

10.1 (1.8)a

---

Resting heart rate, bpm

PRE

102.6 (10.3)a

106.1 (12.1)a

90.5 (15.7)b

POST

86.2 (13.8)b

110.6 (8.4)a

---

Peak heart rate, bpm

PRE

178.2 (18.3)a

177.6 (17.4)a

195.8 (8.9)a

POST

183.6 (10.5)a

178.1 (18.6)a

---

Peak VO2, ml/Kg/min

PRE

27.7 (6.1)a

25.7 (3.1)a

39.9 (7.3)b

POST

31.8 (8.0)b

25.8 (4.2)a

---

Peak speed (Km/h)

PRE

4.4 (0.6)a

4.2 (0.5)a

5.4 (0.9)b

POST

5.2 (0.8)b

4.3 (0.5)a

---

Chronotropic reserve, %

PRE

75.5 (18.7)a

74.8 (17.3)a

96.6 (8.2)b

POST

87.1 (9.0)b*

74.1 (18.9)a

---

Heart rate, Δ%

Rest to VAT

PRE

29.8 (16.6)a

25.3 (12.0)a

60.0 (24.8)b

POST

56.3 (18.7)b

17.0 (9.5)a

---

Rest to RCP

PRE

53.9 (13.7)a

54.9 (24.9)a

97.3 (35.9)b

POST

97.4 (28.6)b

42.8 (17.4)a

---

Rest to Peak

PRE

75.3 (24.8)a

68.9 (22.9)a

122.6 (42.1)b

POST

117.7 (34.3)b

61.5 (16.6)a

---

Heart rate recovery, ΔHRR

ΔHRR1

PRE

25.5 (14.9)a

26.6 (10.0)a

40.2 (6.9)b

POST

41.5 (10.0)b

26.3 (8.0)a

---

ΔHRR2

PRE

36.6 (10.2)a

35.6 (11.8)a

57.8 (8.9)b

POST

62.2 (13.7)b

39.8 (9.7)a

---


Data are expressed as means (SD) (mixed model for repeated measures). Relative change (Δ%) for heart rate was calculated for the intervals between rest to ventilator anaerobic threshold (VAT), rest to respiratory compensation point (RCP), and rest to peak of exercise. Absolute change (Δ) was used to calculate the difference between heart rate at peak exercise and at the first (ΔHRR1) and second minutes (ΔHRR2) after the exercise test. Means with different letters are significantly different from each other (P < 0.05, between- or within-group comparisons). *P = 0.06, within-group comparison. C-SLE, childhood-onset systemic lupus erythematosus; PRE, pre-intervention (baseline), POST, post-intervention; Peak, peak exercise; VO2, oxygen consumption.

Prado et al. Arthritis Research & Therapy 2013 15:R46   doi:10.1186/ar4205

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