Table 2

Regions of interest considered per functional magnetic resonance imaging task

Domain:

Task

Regions of interest


Working memory:

N-back

Frontal, middle + inferior

Anterior cingulate

Precuneus

Parietal, inferior

Anterior default mode (medial prefrontal cortex) 1

Precuneus + posterior cingulate1

Angular gyrus1

Hippocampus + parahippocampus1

Temporal, superior1

Attention:

CTP-IP

Frontal, inferior

Frontal, middle

Insula + temporal, superior

SMA + cingulate, middle

Parietal, inferior + supramarginal gyrus

Fusiform gyrus + occipital, inferior

Frontal mid, inferior + precentral gyrus

Default, anterior (medial prefrontal cortex) 1

Precuneus + posterior cingulate1

Angular gyrus1

Hippocampus + parahippocampus1

Visuo-construction:

VCA

Frontal, inferior

Frontal, middle

Parietal, Inferior + supramarginal gyrus

Fusiform gyrus + occipital, inferior

Precuneus, bilateral

Parietal, superior

Frontal, superior

Frontal, superior medial bilateral

Default, anterior (medial prefrontal cortex)1

Precuneus + posterior cingulate1

Angular gyrus1

Hippocampus + parahippocampus1


All regions chosen prior to analyses and derived from previously published reports (references [15-18]). 1Regions hypothesized to deactivate under the task; otherwise, the region is hypothesized to activate. Unless otherwise indicated, right and left hemisphere portions of each region are considered separately in analyses. CPT-IP, continuous performance task-identical pairs; VCA: visuoconstructive ability; SMA, supplementary motor area.

DiFrancesco et al. Arthritis Research & Therapy 2013 15:R40   doi:10.1186/ar4197

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