Incidence and severity of K/BxN serum transfer-induced arthritis are not reduced in IL-36 receptor (R) knockout (KO) mice. Incidence of arthritis (A), arthritis severity scores (B) and the number of affected paws (C) are shown for WT (n = 10, black line) and IL-36R KO (n = 7, dashed line) mice. (A and C) Results are shown as the mean ± standard error of the mean.
Lamacchia et al. Arthritis Research & Therapy 2013 15:R38 doi:10.1186/ar4192