Figure 4.

CSULGIE incidence rates in the meta-analysis and subsequent large RCTs. *Incidence rate based on 100 patient-years of exposure to drug. CONDOR, Celecoxib vs Omeprazole and Diclofenac in Patients with Osteoarthritis and Rheumatoid Arthritis study; GI-REASONS, Gastrointestinal Randomized Event And Safety Open-Label NSAID Study; nsNSAID, nonselective nonsteroidal antiinflammatory drug.