Additional file 1.
Deletion of the Mmp13 gene in chondrocytes at the postnatal stage has no significant effect on articular and growth plate cartilage morphology. Histological sections from 10-week-old Cre-negative control and matrix metalloproteinase (MMP13) conditional knockout (cKO) mice (Mmp13Col2ER) treated with or without tamoxifen (tamoxifen was administered to two-week-old mice) were stained with Alcian blue/Hematoxylin/Orange G. No significant changes in articular and growth plate cartilage morphology were observed in these mice.
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Wang et al. Arthritis Research & Therapy 2013 15:R5 doi:10.1186/ar4133