Open Access Highly Accessed Research article

Role of ultrasonography in diagnosing early rheumatoid arthritis and remission of rheumatoid arthritis - a systematic review of the literature

David F Ten Cate1*, Jolanda J Luime1, Nanno Swen2, Andreas H Gerards3, Mike H De Jager4, Natalja M Basoski5, Johanna MW Hazes1, Cees J Haagsma6 and Johannes WG Jacobs7

Author Affiliations

1 Rheumatology, Erasmus Medical Center Rotterdam, Dr. Molewaterplein 50-60, Rotterdam, 3015 GE, The Netherlands

2 Rheumatology, Medical Center Alkmaar, Wilhelminalaan 12, Alkmaar, 1815 JD, The Netherlands

3 Rheumatology, Vlietland Hospital Schiedam, Vlietlandplein 2, Schiedam, 3118 JH, The Netherlands

4 Rheumatology, Albert Schweitzer Hospital, Albert Schweitzerplaats 25, Dordrecht, 3318 AT, The Netherlands

5 Rheumatology, Maasstad Hospital, Maasstadweg 21, Rotterdam, 3079 DZ, The Netherlands

6 Rheumatology, Hospital Group Twente, Zilvermeeuw 1, Almelo, 7609 PP, The Netherlands

7 Rheumatology & Clinical Immunology, University Medical Center Utrecht, Heidelberglaan 100, Utrecht, 3584 CX, The Netherlands

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Arthritis Research & Therapy 2013, 15:R4  doi:10.1186/ar4132

Published: 8 January 2013

Additional files

Additional file 1:

Search strategies. Both for the domain of early rheumatoid arthritis (RA) and remission a separate search strategy for PubMed and Embase is presented, as well as a flow chart.

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Additional file 2:

Adaptation of the diagnostic phases (levels) of Sackett and Haynes. Adaptation of Sackett and Haynes phases (levels) of diagnostic questions in diagnostic studies to reflect the clinical relevance of the reviewed studies.

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Additional file 3:

Quality assessment lists. For the domain of early rheumatoid arthritis (RA) we used the Quadas-2, with an extra question on sample size. For the studies evaluating remission, no quality assessment tool was available, therefore we created a quality items list to evaluate these studies.

Format: DOC Size: 79KB Download file

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