Table 2

Adipokines in lean, overweight and obese patients

Lean (group 1)

Overweight (group 2)

Obese (group 3)

Comparison of groups


Baseline

∆15 wks

∆30 wks

Baseline

∆15 wks

∆30 wks

Baseline

∆15 wks

∆30 wks

Groups

At baseline

Change after 15 weeks

Change after 30 weeks

Median (range)

Median (range)

P-valuea

Median (range)

P-valuea

Median (range)

Median (range)

P-valuea

Median (range)

P-valuea

Median (range)

Median (range)

P-valuea

Median (range)

P-valuea

P-valueb

P-valueb

P-valueb


Adipo-nectin

ng/ml

18620.8 (5707.0 to 23038.0)

783.3

(-3501.6 to 4270.7)

488.5 (-1047.7 to 6069.1)

4580.4 (2939.7 to 9634.0)

400.0

(-438.0 to 1681.0)

578.0

(-1764.5 to 1281.3)

4745.5 (2864.9 to 5879.0)

1011.3

(-382.6 to 3273.8)

1206.9

(-1157.4 to 3811.5)

Lean vs overweight

0.013

0.591

0.346

n = 9

P = 0.441

n = 9

P = 0.398

n = 7

n = 26

P = 0.122

n = 25

P = 0.861

n = 25

n = 13

P = 0.133

n = 13

P = 0.214

n = 9

Lean vs obese

0.003

0.794

1.000

Leptin

ng/ml

16012.4 (10250.4 to 25627.3)

2136.2

(-4133.4 to 5400.4)

-4455.8 (-10473.7 to 2250.7)

27658.2 (19222.8 to 45504.1)

1417.0

(-6055.4 to 6858.3)

1760

(-9912.1 to 9778.1)

45300.0 (34456.5 to 86307.4)

5269.7

(-5534.8 to 9055.5)

1446.4

(-3059.4 to 8129.1)

Lean vs overweight

0.067

0.939

0.161

n = 9

P = 0.515

n = 9

P = 0.128

n = 7

n = 26

P = 0.778

n = 25

P = 0.443

n = 25

n = 13

P = 0.422

n = 13

P = 0.594

n = 9

Lean vs obese

<0.001

0.471

0.142

NPY

pg/ml

114.5 (86.6 to 624.6)

19.0

(-10.7 to 98.5)

6.7

122.8 (80.5 to 164.9)

-7.7

(-27.4 to 31.3)

9.0 (-8.2 to 27.3)

113.7 (76.0 to 553.8)

21.8 (1.3 to 225.0)

44.4 (18.3 to 1272.7)

Lean vs overweight

0.82

0.178

0.824

n = 4

P = 0.465

n = 4

P = 0.18

n = 2

n = 16

P = 0.959

n = 16

P = 0.256

n = 15

n = 6

P = 0.075

n = 6

P = 0.043

n = 5

Lean vs obese

0.914

0.762

0.095

Resistin

pg/ml

14768.2 (12312.3 to 27191.5)

927.7

(-3165.5 to 3897.5)

1006.1

(-8555.9 to 4448.6)

14419.1 (13786.6 to 16531.2)

437.3

(-1698.2 to 2634.9)

701.1

(-573.9 to 3872.6)

14951.6 (12671.2 to 20016.0)

1189.2

(-1110.2 to 2292.4)

3110.7

(-534.1 to 4311.0)

Lean vs overweight

0.67

1.000

0.789

n = 9

P = 0.678

n = 9

P = 1.000

n = 7

n = 26

P = 0.465

n = 23

P = 0.051

n = 25

n = 13

P = 0.221

n = 13

P = 0.214

n = 9

Lean vs obese

0.794

0.845

0.837


Serum levels of adiponectin, leptin, NPY and resistin at baseline (0 weeks), change (∆) during training (15 weeks) and change after training (30 weeks). Median values and interquartile range are indicated. aWilcoxon signed rank test. bMann-Whitney U-test. NPY, neuropeptide Y.

Bjersing et al. Arthritis Research & Therapy 2013 15:R34   doi:10.1186/ar4187

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