Table 4

Genotype and the radiographic severity in patients with OA

Genotype

KL = < 3, number of patients

%

KL > 3, number of patients

%

Global P-value

Adjusted OR

95% CI

Adjusted P-value


-156/G/GG

GG

92

26.21

91

22.81

0.462

1

GGG

166

47.29

206

51.63

0.787

0.564

1.178

0.223

GGGG

93

26.50

102

25.56

0.916

0.638

1.376

0.653

G

350

49.86

388

48.62

1

GG

352

50.14

410

51.38

0.934

0.786

1.186

0.648

-443C/T

CC

88

25.07

79

19.80

< 0.001

1

CT

176

50.14

188

47.12

0.816

0.537

1.264

0.352

TT

87

24.79

132

33.08

0.664

0.365

0.879

0.011

C

352

50.14

346

43.36

1

T

350

49.86

452

56.64

0.659

0.647

0.948

0.008

-66T/G

TT

97

27.64

91

22.81

0.462

1

TG

158

45.01

191

47.87

0.865

0.587

1.234

0.174

GG

96

27.35

117

29.32

0.757

0.438

0.944

0.023

T

332

47.29

373

46.74

1

G

370

52.71

425

53.26

0.7326

0.668

0.973

0.017


KL, Kellgren-Lawrence grade

Jiang et al. Arthritis Research & Therapy 2013 15:R3   doi:10.1186/ar4129

Open Data