Table 4 |
||||||||||
|
Genotype and the radiographic severity in patients with OA |
||||||||||
|
Genotype |
KL = < 3, number of patients |
% |
KL > 3, number of patients |
% |
Global P-value |
Adjusted OR |
95% CI |
Adjusted P-value |
||
|
|
||||||||||
|
-156/G/GG |
GG |
92 |
26.21 |
91 |
22.81 |
0.462 |
1 |
|||
|
GGG |
166 |
47.29 |
206 |
51.63 |
0.787 |
0.564 |
1.178 |
0.223 |
||
|
GGGG |
93 |
26.50 |
102 |
25.56 |
0.916 |
0.638 |
1.376 |
0.653 |
||
|
G |
350 |
49.86 |
388 |
48.62 |
1 |
|||||
|
GG |
352 |
50.14 |
410 |
51.38 |
0.934 |
0.786 |
1.186 |
0.648 |
||
|
-443C/T |
CC |
88 |
25.07 |
79 |
19.80 |
< 0.001 |
1 |
|||
|
CT |
176 |
50.14 |
188 |
47.12 |
0.816 |
0.537 |
1.264 |
0.352 |
||
|
TT |
87 |
24.79 |
132 |
33.08 |
0.664 |
0.365 |
0.879 |
0.011 |
||
|
C |
352 |
50.14 |
346 |
43.36 |
1 |
|||||
|
T |
350 |
49.86 |
452 |
56.64 |
0.659 |
0.647 |
0.948 |
0.008 |
||
|
-66T/G |
TT |
97 |
27.64 |
91 |
22.81 |
0.462 |
1 |
|||
|
TG |
158 |
45.01 |
191 |
47.87 |
0.865 |
0.587 |
1.234 |
0.174 |
||
|
GG |
96 |
27.35 |
117 |
29.32 |
0.757 |
0.438 |
0.944 |
0.023 |
||
|
T |
332 |
47.29 |
373 |
46.74 |
1 |
|||||
|
G |
370 |
52.71 |
425 |
53.26 |
0.7326 |
0.668 |
0.973 |
0.017 |
||
|
|
||||||||||
|
KL, Kellgren-Lawrence grade |
||||||||||
|
Jiang et al. Arthritis Research & Therapy 2013 15:R3 doi:10.1186/ar4129 |
||||||||||
