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Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies

Lucas A Smolders, Björn P Meij, David Onis, Frank M Riemers, Niklas Bergknut, Richard Wubbolts, Guy CM Grinwis, Martin Houweling, Marian JA Groot Koerkamp, Dik van Leenen, Frank CP Holstege, Herman AW Hazewinkel, Laura B Creemers, Louis C Penning and Marianna A Tryfonidou*

Arthritis Research & Therapy 2013, 15:R23  doi:10.1186/ar4157


See related editorial by Erwin, http://arthritis-research.com/content/15/2/113

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