Additional file 1.

The cell viability of PI3K, Akt, and NF-κB inhibitors in human synovial fibroblasts. OASFs were treated with Wortmannin, Ly294002, Akt inhibitor, PDTC, or TPCK for 24 hours. The cell viability was examined by MTT assay. MTT, 3-(4,5-dmethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; OASFs, osteoarthritis synovial fibroblasts; PDTC, pyrrolidine-dithiocarbamate; TPCK, L-1-tosylamido-2-phenylenylethyl chloromethyl ketone.

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Hou et al. Arthritis Research & Therapy 2013 15:R19   doi:10.1186/ar4151