Table 1

Baseline characteristics of patients in the longitudinal pediatric- and adult-onset systemic lupus erythematosus (pSLE and aSLE) cohorts*

pSLE

Pediatric controls

aSLE

Adult controls

Sex, ratio, male:female,

10:32

10:12

2:21

16:24

Ethnicity/race, n (%)

Hispanic

21 (50)

5 (23)

2 (9)

6 (15)

Asian

10 (24)

10 (45)

2 (9)

13 (32)

Caucasian

5 (12)

6 (27)

13 (56)

16 (40)

African-American

4 (9)

1 (5)

4 (17)

4 (10)

Other/Mixed

2 (5)

0

2 (9)

1 (3)

Age, years

15.9 ± 3.5

20.2 ± 1.3

42 ± 15

41 ± 10

Age at diagnosis, years

12.7 ± 4.1

32 ± 15

Disease duration, years^†

3.1 ± 3

7.9 ± 8.6

SLEDAI, mean (range)

2.0 (0, 15)

3.0 (0, 12)

SDI, mean (range)

0.9 (0, 5)

0.9 (0, 2)

Glomerulonephritis, n (%)^††

30 (71)

5 (22)

Class II

0

0

Class III

0

0

Class IV

17 (40)

4 (17)

Class V

6 (14)

0

Mixed

5 (12)

0

*Except where indicated otherwise, values are expressed as the mean ± SD and were obtained at the time of study entry. SLEDAI, Systemic Lupus Erythematosus Disease Activity Index; SDI, Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index; Glomerulonephritis classification as per the International Society of Nephrology/Renal Pathology Society. There was no biopsy done on one aSLE patient with clinical criteria of SLE renal disease. ^†P = 0.002 in pSLE compared with aSLE; ^††P = 0.0005 in pSLE compared with aSLE.

Rullo et al. Arthritis Research & Therapy 2013 15:R18   doi:10.1186/ar4150