Figure 1.

Autoantibodies found in early systemic lupus erythematosus. Typical systemic lupus erythematosus-associated autoantibodies are in black, those that are usually associated with other diseases are in blue letters. Overall, the wide antibody variety points to more generalized B-cell autoreactivity underlying systemic lupus erythematosus. dsDNA, double-stranded DNA; PCNA, proliferating cell nuclear antigen; TPO, thyroid peroxidase.