Arthritis Research & Therapy | Volume 15 Issue 1

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	Volume 15 Issue 1
	Comment
	Editorial (Auto)immunity to cartilage matrix proteins - a time bomb? Raimund W Kinne Arthritis Research & Therapy 2012, 15:101 (21 January 2013) Abstract \| Full text \| PDF
	Editorial Lots of autoantibodies equal lupus? Martin Aringer, Edward Vital Arthritis Research & Therapy 2013, 15:102 (22 January 2013) Abstract \| Full text \| PDF \| PubMed
	Editorial IgG4-related disease: why high IgG4 and fibrosis? Takao Koike Arthritis Research & Therapy 2013, 15:103 (25 January 2013) Abstract \| Full text \| PDF \| PubMed
	Editorial Tools for monitoring remission in rheumatoid arthritis: any will do, let's just pick one and start measuring Yusuf Yazici, Ismail Simsek Arthritis Research & Therapy 2013, 15:104 (28 January 2013) Abstract \| Full text \| PDF \| PubMed
	Editorial Adult-onset immunodeficiency - why is it important in rheumatology? Hans-Hartmut Peter Arthritis Research & Therapy 2012, 15:105 (30 January 2013) Abstract \| Full text \| PDF
	Editorial The butterfly rash of lupus: An example of aposematism? David S Pisetsky Arthritis Research & Therapy 2013, 15:106 (19 February 2013) Abstract \| Full text \| PDF \| PubMed
	Editorial To target or not to target APRIL in systemic lupus erythematosus: that is the question! Jacques Morel, Michael Hahne Arthritis Research & Therapy 2013, 15:107 (25 February 2013) Abstract \| Full text \| PDF \| PubMed
	Commentary Enhancing the reporting and transparency of rheumatology research: a guide to reporting guidelines Robin Christensen, Henning Bliddal, Marius Henriksen Arthritis Research & Therapy 2013, 15:109 (28 February 2013) Abstract \| Full text \| PDF \| PubMed
	Review
	Review MicroRNA control in the development of systemic autoimmunity Ruozhen Hu, Ryan M O'Connell Arthritis Research & Therapy 2013, 15:202 (25 January 2013) Abstract \| Full text \| PDF \| PubMed
	Review Dissecting complex epigenetic alterations in human lupus Dipak R Patel, Bruce C Richardson Arthritis Research & Therapy 2012, 15:201 (29 January 2013) Abstract \| Full text \| PDF
	Review Implantable sensor technology: measuring bone and joint biomechanics of daily life in vivo Darryl D D'Lima, Benjamin J Fregly, Clifford W Colwell Arthritis Research & Therapy 2013, 15:203 (31 January 2013) Abstract \| Full text \| PDF \| PubMed
	Review Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis Ranjeny Thomas Arthritis Research & Therapy 2013, 15:204 (4 February 2013) Abstract \| Full text \| PDF \| PubMed
	Review The role of the circadian clock in rheumatoid arthritis Julie E Gibbs, David W Ray Arthritis Research & Therapy 2013, 15:205 (21 February 2013) Abstract \| Full text \| PDF \| PubMed
	Review CD154: the atherosclerotic risk factor in rheumatoid arthritis? Ghada S Hassan, Daniel Yacoub, Nada Alaaeddine, Amal Nadiri, Yahye Merhi, Walid Mourad Arthritis Research & Therapy 2013, 15:206 (22 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research
	Research article Persistence of antibody response 1.5 years after vaccination using 7-valent pneumococcal conjugate vaccine in patients with arthritis treated with different antirheumatic drugs Meliha Crnkic Kapetanovic, Tore Saxne, Lennart Truedsson, Pierre Geborek Arthritis Research & Therapy 2013, 15:R1 (4 January 2013) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	Research article Low-field magnetic resonance imaging study on carpal arthritis in systemic sclerosis - low-grade erosive arthritis of carpal bones is an unexpected and frequent disease manifestation Elif Akbayrak, Robert Dinser, Ulf Müller-Ladner, Ingo H Tarner Arthritis Research & Therapy 2013, 15:R2 (4 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article OPN gene polymorphisms influence the risk of knee OA and OPN levels in synovial fluid in a Chinese population Yongqing Jiang, Meng Yao, Qingpeng Liu, Changwei Zhou Arthritis Research & Therapy 2013, 15:R3 (5 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Role of ultrasonography in diagnosing early rheumatoid arthritis and remission of rheumatoid arthritis - a systematic review of the literature David F Ten Cate, Jolanda J Luime, Nanno Swen, Andreas H Gerards, Mike H De Jager, Natalja M Basoski, Johanna MW Hazes, Cees J Haagsma, Johannes WG Jacobs Arthritis Research & Therapy 2013, 15:R4 (8 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Ultrasonography has added value to clinical examination in diagnosing early rheumatoid arthritis and assessing remission, which could facilitate the provision of earlier and more effective treatments.
	Research article MMP13 is a critical target gene during the progression of osteoarthritis Meina Wang, Erik R Sampson, Hongting Jin, Jia Li, Qiao H Ke, Hee-Jeong Im, Di Chen Arthritis Research & Therapy 2013, 15:R5 (8 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Patient-level pooled analysis of adjudicated gastrointestinal outcomes in celecoxib clinical trials: meta-analysis of 51,000 patients enrolled in 52 randomized trials Andrew Moore, Geoffrey Makinson, Chunming Li Arthritis Research & Therapy 2013, 15:R6 (8 January 2013) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	Research article Atherosclerotic cardiovascular disease and dermatomyositis: an analysis of the Nationwide Inpatient Sample survey Eleni Linos, David Fiorentino, Bharathi Lingala, Eswar Krishnan, Lorinda Chung Arthritis Research & Therapy 2013, 15:R7 (8 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Patients suffering from both dermatomyositis and an atherosclerotic cardiovascular disease (CVD) are twice as likely to die during inpatient stay compared to controls with CVD, and dermatomyositis patients without CVD.
	Research article Prognostic impact of coronary microcirculation abnormalities in systemic sclerosis: a prospective study to evaluate the role of non-invasive tests Alessandra Vacca, Roberta Montisci, Pietro Garau, Paolo Siotto, Matteo Piga, Alberto Cauli, Massimo Ruscazio, Luigi Meloni, Sabino Iliceto, Alessandro Mathieu Arthritis Research & Therapy 2013, 15:R8 (9 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Predictors of Chikungunya rheumatism: a prognostic survey ancillary to the TELECHIK cohort study Patrick Gérardin, Adrian Fianu, Alain Michault, Corinne Mussard, Karim Boussaïd, Olivier Rollot, Philippe Grivard, Somar Kassab, Eric Bouquillard, Gianandrea Borgherini, Bernard-Alex Gaüzère, Denis Malvy, Gérard Bréart, François Favier Arthritis Research & Therapy 2013, 15:R9 (9 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis Keiko Aida-Yasuoka, Christine Peoples, Hidekata Yasuoka, Pamela Hershberger, Katelynn Thiel, Jane A Cauley, Thomas A Medsger, Carol A Feghali-Bostwick Arthritis Research & Therapy 2013, 15:R10 (10 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Association of the AIRE gene with susceptibility to rheumatoid arthritis in a European population: a case control study José-Raúl García-Lozano, Belén Torres-Agrela, Marco-Antonio Montes-Cano, Lourdes Ortiz-Fernández, Marta Conde-Jaldón, María Teruel, Alicia García, Antonio Núñez-Roldán, Javier Martín, María-Francisca González-Escribano Arthritis Research & Therapy 2013, 15:R11 (15 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article The spectrum of renal thrombotic microangiopathy in lupus nephritis Di Song, Li-hua Wu, Feng-mei Wang, Xiao-wei Yang, Di Zhu, Min Chen, Feng Yu, Gang Liu, Ming-hui Zhao Arthritis Research & Therapy 2013, 15:R12 (15 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Disease severity in K/BxN serum transfer-induced arthritis is not affected by IL-33 deficiency Praxedis Martin, Dominique Talabot-Ayer, Christian Seemayer, Solenne Vigne, Céline Lamacchia, Emiliana Rodriguez, Axel Finckh, Dirk E Smith, Cem Gabay, Gaby Palmer Arthritis Research & Therapy 2013, 15:R13 (16 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Scoring radiographic progression in ankylosing spondylitis: should we use the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) or the Radiographic Ankylosing Spondylitis Spinal Score (RASSS)? Sofia Ramiro, Astrid van Tubergen, Carmen Stolwijk, Robert Landewé, Filip van de Bosch, Maxime Dougados, Désirée van der Heijde Arthritis Research & Therapy 2013, 15:R14 (17 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Expression of regulatory receptors on γδ T Cells and their cytokine production in Behcet's disease Gunes Parlakgul, Ekin Guney, Burak Erer, Zeki Kılıcaslan, Haner Direskeneli, Ahmet Gul, Guher Saruhan-Direskeneli Arthritis Research & Therapy 2013, 15:R15 (21 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Anti-cyclic citrullinated peptide antibody titer predicts time to rheumatoid arthritis onset in patients with undifferentiated arthritis: results from a 2-year prospective study Nicola Bizzaro, Elena Bartoloni, Gabriella Morozzi, Stefania Manganelli, Valeria Riccieri, Paola Sabatini, Matteo Filippini, Marilina Tampoia, Antonella Afeltra, Giandomenico Sebastiani, Claudia Alpini, Vittorio Bini, Onelia Bistoni, Alessia Alunno, Roberto Gerli, the Forum Interdisciplinare per la Ricerca nelle Malattie Autoimmuni (FIRMA Group) Arthritis Research & Therapy 2013, 15:R16 (22 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Impaired beta cell function is present in nondiabetic rheumatoid arthritis patients Iván Ferraz-Amaro, Jose A García-Dopico, Lilian Medina-Vega, Miguel A González-Gay, Federico Díaz-González Arthritis Research & Therapy 2013, 15:R17 (22 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Plasma levels of osteopontin identify patients at risk for organ damage in systemic lupus erythematosus Ornella J Rullo, Jennifer MP Woo, Miriam F Parsa, Alice DC Hoftman, Paul Maranian, David A Elashoff, Timothy B Niewold, Jennifer M Grossman, Bevra H Hahn, Maureen McMahon, Deborah K McCurdy, Betty P Tsao Arthritis Research & Therapy 2013, 15:R18 (23 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article CCN4 induces IL-6 production through αvβ5 receptor, PI3K, Akt, and NF-κB singling pathway in human synovial fibroblasts Chun-Han Hou, Chih-Hsin Tang, Chin-Jung Hsu, Sheng-Mon Hou, Ju-Fang Liu Arthritis Research & Therapy 2013, 15:R19 (23 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article A rheumatoid factor paradox: inhibition of rituximab effector function Jonathan D Jones, Irene Shyu, Marianna M Newkirk, William FC Rigby Arthritis Research & Therapy 2013, 15:R20 (25 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article High prevalence of spondyloarthritis and ankylosing spondylitis among familial Mediterranean fever patients and their first-degree relatives: further evidence for the connection Servet Akar, Ozgul Soysal, Ali Balci, Dilek Solmaz, Vedat Gerdan, Fatos Onen, Mehmet Tunca, Nurullah Akkoc Arthritis Research & Therapy 2013, 15:R21 (28 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Intra-articular delivery of adipose derived stromal cells attenuates osteoarthritis progression in an experimental rabbit model Giovanna Desando, Carola Cavallo, Federica Sartoni, Lucia Martini, Annapaola Parrilli, Francesca Veronesi, Milena Fini, Roberto Giardino, Andrea Facchini, Brunella Grigolo Arthritis Research & Therapy 2013, 15:R22 (29 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary Adipose derived stromal cells (ASC) promote repair of cartilage and inhibit progression of osteoarthritis (OA) in an experimental rabbit model, highlighting ASC therapy as a potential tool to treat OA.
	Research article Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies Lucas A Smolders, Björn P Meij, David Onis, Frank M Riemers, Niklas Bergknut, Richard Wubbolts, Guy CM Grinwis, Martin Houweling, Marian JA Groot Koerkamp, Dik van Leenen, Frank CP Holstege, Herman AW Hazewinkel, Laura B Creemers, Louis C Penning, Marianna A Tryfonidou Arthritis Research & Therapy 2013, 15:R23 (29 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Characterisation of fibroblast-like synoviocytes from a murine model of joint inflammation Rowan S Hardy, Claudia Hülso, Yingling Liu, Sylvia J Gasparini, Colette Fong-Yee, Jinwen Tu, Shihani Stoner, Paul M Stewart, Karim Raza, Mark S Cooper, Markus J Seibel, Hong Zhou Arthritis Research & Therapy 2013, 15:R24 (29 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Rilonacept in the treatment of acute gouty arthritis: a randomized, controlled clinical trial using indomethacin as the active comparator Robert A Terkeltaub, H Ralph Schumacher, John D Carter, Herbert SB Baraf, Robert R Evans, Jian Wang, Shirletta King-Davis, Steven P Weinstein Arthritis Research & Therapy 2013, 15:R25 (1 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Treatment with indomethacin alone in patients with acute gout flare is more effective than treatment with rilonacept and no greater pain relief is provided when used in combination with rilonacept.
	Research article Regulatory effect of calcineurin inhibitor, tacrolimus, on IL-6/sIL-6R-mediated RANKL expression through JAK2-STAT3-SOCS3 signaling pathway in fibroblast-like synoviocytes Jung-Yoon Choe, Ki-Yeun Park, Sung-Hoon Park, Sang-Il Lee, Seong-Kyu Kim Arthritis Research & Therapy 2013, 15:R26 (13 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Joint damage in rheumatoid arthritis: assessment of a new scoring method Alexander Pfeil, Peter Oelzner, Klaus Bornholdt, Andreas Hansch, Gabriele Lehmann, Diane M Renz, Gunter Wolf, Joachim Böttcher Arthritis Research & Therapy 2013, 15:R27 (13 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes Tetsuya Matsukawa, Tadahiro Sakai, Tomo Yonezawa, Hideki Hiraiwa, Takashi Hamada, Motoshige Nakashima, Yohei Ono, Shinya Ishizuka, Hiroyuki Nakahara, Martin K Lotz, Hiroshi Asahara, Naoki Ishiguro Arthritis Research & Therapy 2013, 15:R28 (13 February 2013) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	Research article Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis Akihiko Hasegawa, Hiroyuki Nakahara, Mitsuo Kinoshita, Hiroshi Asahara, James Koziol, Martin K Lotz Arthritis Research & Therapy 2013, 15:R29 (14 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Clinical characteristics in subjects with NLRP3 V198M diagnosed at a single UK center and a review of the literature Dorota M Rowczenio, Hadija Trojer, Tonia Russell, Anna Baginska, Thirusha Lane, Nicola M Stewart, Julian D Gillmore, Philip N Hawkins, Patricia Woo, Bozena Mikoluc, Helen J Lachmann Arthritis Research & Therapy 2013, 15:R30 (19 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article IL-17-mediated Bcl-2 expression regulates survival of fibroblast-like synoviocytes in rheumatoid arthritis through STAT3 activation Seon-Yeong Lee, Seung-Ki Kwok, Hye-Jin Son, Jun-Geol Ryu, Eun-Kyung Kim, Hye-Jwa Oh, Mi-La Cho, Ji Ju, Sung-Hwan Park, Ho-Youn Kim Arthritis Research & Therapy 2013, 15:R31 (20 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Periodic knee injections of collagen tripeptide delay cartilage degeneration in rabbit experimental osteoarthritis Takuya Naraoka, Yasuyuki Ishibashi, Eiichi Tsuda, Yuji Yamamoto, Tomomi Kusumi, Satoshi Toh Arthritis Research & Therapy 2013, 15:R32 (22 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article The schedule of administration of canakinumab in cryopyrin associated periodic syndrome is driven by the phenotype severity rather than the age Roberta Caorsi, Loredana Lepore, Francesco Zulian, Maria Alessio, Achille Stabile, Antonella Insalaco, Martina Finetti, Antonella Battagliese, Giorgia Martini, Chiara Bibalo, Alberto Martini, Marco Gattorno Arthritis Research & Therapy 2013, 15:R33 (26 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Exercise and obesity in fibromyalgia: beneficial roles of IGF-1 and resistin? Jan L Bjersing, Malin Erlandsson, Maria I Bokarewa, Kaisa Mannerkorpi Arthritis Research & Therapy 2013, 15:R34 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice Olivia Weigert, Caroline von Spee, Reinmar Undeutsch, Lutz Kloke, Jens Y Humrich, Gabriela Riemekasten Arthritis Research & Therapy 2013, 15:R35 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Urinary CD8⁺T-cell counts discriminate between active and inactive lupus nephritis Sebastian Dolff, Wayel H Abdulahad, Suzanne Arends, Marcory CRF van Dijk, Pieter C Limburg, Cees GM Kallenberg, Marc Bijl Arthritis Research & Therapy 2013, 15:R36 (27 February 2013) Abstract \| Full text \| PDF \| PubMed

	Volume 15 Issue 1
	Comment
	Editorial (Auto)immunity to cartilage matrix proteins - a time bomb? Raimund W Kinne Arthritis Research & Therapy 2012, 15:101 (21 January 2013) Abstract \| Full text \| PDF
	Editorial Lots of autoantibodies equal lupus? Martin Aringer, Edward Vital Arthritis Research & Therapy 2013, 15:102 (22 January 2013) Abstract \| Full text \| PDF \| PubMed
	Editorial IgG4-related disease: why high IgG4 and fibrosis? Takao Koike Arthritis Research & Therapy 2013, 15:103 (25 January 2013) Abstract \| Full text \| PDF \| PubMed
	Editorial Tools for monitoring remission in rheumatoid arthritis: any will do, let's just pick one and start measuring Yusuf Yazici, Ismail Simsek Arthritis Research & Therapy 2013, 15:104 (28 January 2013) Abstract \| Full text \| PDF \| PubMed
	Editorial Adult-onset immunodeficiency - why is it important in rheumatology? Hans-Hartmut Peter Arthritis Research & Therapy 2012, 15:105 (30 January 2013) Abstract \| Full text \| PDF
	Editorial The butterfly rash of lupus: An example of aposematism? David S Pisetsky Arthritis Research & Therapy 2013, 15:106 (19 February 2013) Abstract \| Full text \| PDF \| PubMed
	Editorial To target or not to target APRIL in systemic lupus erythematosus: that is the question! Jacques Morel, Michael Hahne Arthritis Research & Therapy 2013, 15:107 (25 February 2013) Abstract \| Full text \| PDF \| PubMed
	Commentary Enhancing the reporting and transparency of rheumatology research: a guide to reporting guidelines Robin Christensen, Henning Bliddal, Marius Henriksen Arthritis Research & Therapy 2013, 15:109 (28 February 2013) Abstract \| Full text \| PDF \| PubMed
	Review
	Review MicroRNA control in the development of systemic autoimmunity Ruozhen Hu, Ryan M O'Connell Arthritis Research & Therapy 2013, 15:202 (25 January 2013) Abstract \| Full text \| PDF \| PubMed
	Review Dissecting complex epigenetic alterations in human lupus Dipak R Patel, Bruce C Richardson Arthritis Research & Therapy 2012, 15:201 (29 January 2013) Abstract \| Full text \| PDF
	Review Implantable sensor technology: measuring bone and joint biomechanics of daily life in vivo Darryl D D'Lima, Benjamin J Fregly, Clifford W Colwell Arthritis Research & Therapy 2013, 15:203 (31 January 2013) Abstract \| Full text \| PDF \| PubMed
	Review Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis Ranjeny Thomas Arthritis Research & Therapy 2013, 15:204 (4 February 2013) Abstract \| Full text \| PDF \| PubMed
	Review The role of the circadian clock in rheumatoid arthritis Julie E Gibbs, David W Ray Arthritis Research & Therapy 2013, 15:205 (21 February 2013) Abstract \| Full text \| PDF \| PubMed
	Review CD154: the atherosclerotic risk factor in rheumatoid arthritis? Ghada S Hassan, Daniel Yacoub, Nada Alaaeddine, Amal Nadiri, Yahye Merhi, Walid Mourad Arthritis Research & Therapy 2013, 15:206 (22 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research
	Research article Persistence of antibody response 1.5 years after vaccination using 7-valent pneumococcal conjugate vaccine in patients with arthritis treated with different antirheumatic drugs Meliha Crnkic Kapetanovic, Tore Saxne, Lennart Truedsson, Pierre Geborek Arthritis Research & Therapy 2013, 15:R1 (4 January 2013) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	Research article Low-field magnetic resonance imaging study on carpal arthritis in systemic sclerosis - low-grade erosive arthritis of carpal bones is an unexpected and frequent disease manifestation Elif Akbayrak, Robert Dinser, Ulf Müller-Ladner, Ingo H Tarner Arthritis Research & Therapy 2013, 15:R2 (4 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article OPN gene polymorphisms influence the risk of knee OA and OPN levels in synovial fluid in a Chinese population Yongqing Jiang, Meng Yao, Qingpeng Liu, Changwei Zhou Arthritis Research & Therapy 2013, 15:R3 (5 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Role of ultrasonography in diagnosing early rheumatoid arthritis and remission of rheumatoid arthritis - a systematic review of the literature David F Ten Cate, Jolanda J Luime, Nanno Swen, Andreas H Gerards, Mike H De Jager, Natalja M Basoski, Johanna MW Hazes, Cees J Haagsma, Johannes WG Jacobs Arthritis Research & Therapy 2013, 15:R4 (8 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Ultrasonography has added value to clinical examination in diagnosing early rheumatoid arthritis and assessing remission, which could facilitate the provision of earlier and more effective treatments.
	Research article MMP13 is a critical target gene during the progression of osteoarthritis Meina Wang, Erik R Sampson, Hongting Jin, Jia Li, Qiao H Ke, Hee-Jeong Im, Di Chen Arthritis Research & Therapy 2013, 15:R5 (8 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Patient-level pooled analysis of adjudicated gastrointestinal outcomes in celecoxib clinical trials: meta-analysis of 51,000 patients enrolled in 52 randomized trials Andrew Moore, Geoffrey Makinson, Chunming Li Arthritis Research & Therapy 2013, 15:R6 (8 January 2013) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	Research article Atherosclerotic cardiovascular disease and dermatomyositis: an analysis of the Nationwide Inpatient Sample survey Eleni Linos, David Fiorentino, Bharathi Lingala, Eswar Krishnan, Lorinda Chung Arthritis Research & Therapy 2013, 15:R7 (8 January 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Patients suffering from both dermatomyositis and an atherosclerotic cardiovascular disease (CVD) are twice as likely to die during inpatient stay compared to controls with CVD, and dermatomyositis patients without CVD.
	Research article Prognostic impact of coronary microcirculation abnormalities in systemic sclerosis: a prospective study to evaluate the role of non-invasive tests Alessandra Vacca, Roberta Montisci, Pietro Garau, Paolo Siotto, Matteo Piga, Alberto Cauli, Massimo Ruscazio, Luigi Meloni, Sabino Iliceto, Alessandro Mathieu Arthritis Research & Therapy 2013, 15:R8 (9 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Predictors of Chikungunya rheumatism: a prognostic survey ancillary to the TELECHIK cohort study Patrick Gérardin, Adrian Fianu, Alain Michault, Corinne Mussard, Karim Boussaïd, Olivier Rollot, Philippe Grivard, Somar Kassab, Eric Bouquillard, Gianandrea Borgherini, Bernard-Alex Gaüzère, Denis Malvy, Gérard Bréart, François Favier Arthritis Research & Therapy 2013, 15:R9 (9 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis Keiko Aida-Yasuoka, Christine Peoples, Hidekata Yasuoka, Pamela Hershberger, Katelynn Thiel, Jane A Cauley, Thomas A Medsger, Carol A Feghali-Bostwick Arthritis Research & Therapy 2013, 15:R10 (10 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Association of the AIRE gene with susceptibility to rheumatoid arthritis in a European population: a case control study José-Raúl García-Lozano, Belén Torres-Agrela, Marco-Antonio Montes-Cano, Lourdes Ortiz-Fernández, Marta Conde-Jaldón, María Teruel, Alicia García, Antonio Núñez-Roldán, Javier Martín, María-Francisca González-Escribano Arthritis Research & Therapy 2013, 15:R11 (15 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article The spectrum of renal thrombotic microangiopathy in lupus nephritis Di Song, Li-hua Wu, Feng-mei Wang, Xiao-wei Yang, Di Zhu, Min Chen, Feng Yu, Gang Liu, Ming-hui Zhao Arthritis Research & Therapy 2013, 15:R12 (15 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Disease severity in K/BxN serum transfer-induced arthritis is not affected by IL-33 deficiency Praxedis Martin, Dominique Talabot-Ayer, Christian Seemayer, Solenne Vigne, Céline Lamacchia, Emiliana Rodriguez, Axel Finckh, Dirk E Smith, Cem Gabay, Gaby Palmer Arthritis Research & Therapy 2013, 15:R13 (16 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Scoring radiographic progression in ankylosing spondylitis: should we use the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) or the Radiographic Ankylosing Spondylitis Spinal Score (RASSS)? Sofia Ramiro, Astrid van Tubergen, Carmen Stolwijk, Robert Landewé, Filip van de Bosch, Maxime Dougados, Désirée van der Heijde Arthritis Research & Therapy 2013, 15:R14 (17 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Expression of regulatory receptors on γδ T Cells and their cytokine production in Behcet's disease Gunes Parlakgul, Ekin Guney, Burak Erer, Zeki Kılıcaslan, Haner Direskeneli, Ahmet Gul, Guher Saruhan-Direskeneli Arthritis Research & Therapy 2013, 15:R15 (21 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Anti-cyclic citrullinated peptide antibody titer predicts time to rheumatoid arthritis onset in patients with undifferentiated arthritis: results from a 2-year prospective study Nicola Bizzaro, Elena Bartoloni, Gabriella Morozzi, Stefania Manganelli, Valeria Riccieri, Paola Sabatini, Matteo Filippini, Marilina Tampoia, Antonella Afeltra, Giandomenico Sebastiani, Claudia Alpini, Vittorio Bini, Onelia Bistoni, Alessia Alunno, Roberto Gerli, the Forum Interdisciplinare per la Ricerca nelle Malattie Autoimmuni (FIRMA Group) Arthritis Research & Therapy 2013, 15:R16 (22 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Impaired beta cell function is present in nondiabetic rheumatoid arthritis patients Iván Ferraz-Amaro, Jose A García-Dopico, Lilian Medina-Vega, Miguel A González-Gay, Federico Díaz-González Arthritis Research & Therapy 2013, 15:R17 (22 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Plasma levels of osteopontin identify patients at risk for organ damage in systemic lupus erythematosus Ornella J Rullo, Jennifer MP Woo, Miriam F Parsa, Alice DC Hoftman, Paul Maranian, David A Elashoff, Timothy B Niewold, Jennifer M Grossman, Bevra H Hahn, Maureen McMahon, Deborah K McCurdy, Betty P Tsao Arthritis Research & Therapy 2013, 15:R18 (23 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article CCN4 induces IL-6 production through αvβ5 receptor, PI3K, Akt, and NF-κB singling pathway in human synovial fibroblasts Chun-Han Hou, Chih-Hsin Tang, Chin-Jung Hsu, Sheng-Mon Hou, Ju-Fang Liu Arthritis Research & Therapy 2013, 15:R19 (23 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article A rheumatoid factor paradox: inhibition of rituximab effector function Jonathan D Jones, Irene Shyu, Marianna M Newkirk, William FC Rigby Arthritis Research & Therapy 2013, 15:R20 (25 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article High prevalence of spondyloarthritis and ankylosing spondylitis among familial Mediterranean fever patients and their first-degree relatives: further evidence for the connection Servet Akar, Ozgul Soysal, Ali Balci, Dilek Solmaz, Vedat Gerdan, Fatos Onen, Mehmet Tunca, Nurullah Akkoc Arthritis Research & Therapy 2013, 15:R21 (28 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Intra-articular delivery of adipose derived stromal cells attenuates osteoarthritis progression in an experimental rabbit model Giovanna Desando, Carola Cavallo, Federica Sartoni, Lucia Martini, Annapaola Parrilli, Francesca Veronesi, Milena Fini, Roberto Giardino, Andrea Facchini, Brunella Grigolo Arthritis Research & Therapy 2013, 15:R22 (29 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology \| Editor’s summary Adipose derived stromal cells (ASC) promote repair of cartilage and inhibit progression of osteoarthritis (OA) in an experimental rabbit model, highlighting ASC therapy as a potential tool to treat OA.
	Research article Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies Lucas A Smolders, Björn P Meij, David Onis, Frank M Riemers, Niklas Bergknut, Richard Wubbolts, Guy CM Grinwis, Martin Houweling, Marian JA Groot Koerkamp, Dik van Leenen, Frank CP Holstege, Herman AW Hazewinkel, Laura B Creemers, Louis C Penning, Marianna A Tryfonidou Arthritis Research & Therapy 2013, 15:R23 (29 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Characterisation of fibroblast-like synoviocytes from a murine model of joint inflammation Rowan S Hardy, Claudia Hülso, Yingling Liu, Sylvia J Gasparini, Colette Fong-Yee, Jinwen Tu, Shihani Stoner, Paul M Stewart, Karim Raza, Mark S Cooper, Markus J Seibel, Hong Zhou Arthritis Research & Therapy 2013, 15:R24 (29 January 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Rilonacept in the treatment of acute gouty arthritis: a randomized, controlled clinical trial using indomethacin as the active comparator Robert A Terkeltaub, H Ralph Schumacher, John D Carter, Herbert SB Baraf, Robert R Evans, Jian Wang, Shirletta King-Davis, Steven P Weinstein Arthritis Research & Therapy 2013, 15:R25 (1 February 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Treatment with indomethacin alone in patients with acute gout flare is more effective than treatment with rilonacept and no greater pain relief is provided when used in combination with rilonacept.
	Research article Regulatory effect of calcineurin inhibitor, tacrolimus, on IL-6/sIL-6R-mediated RANKL expression through JAK2-STAT3-SOCS3 signaling pathway in fibroblast-like synoviocytes Jung-Yoon Choe, Ki-Yeun Park, Sung-Hoon Park, Sang-Il Lee, Seong-Kyu Kim Arthritis Research & Therapy 2013, 15:R26 (13 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Joint damage in rheumatoid arthritis: assessment of a new scoring method Alexander Pfeil, Peter Oelzner, Klaus Bornholdt, Andreas Hansch, Gabriele Lehmann, Diane M Renz, Gunter Wolf, Joachim Böttcher Arthritis Research & Therapy 2013, 15:R27 (13 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes Tetsuya Matsukawa, Tadahiro Sakai, Tomo Yonezawa, Hideki Hiraiwa, Takashi Hamada, Motoshige Nakashima, Yohei Ono, Shinya Ishizuka, Hiroyuki Nakahara, Martin K Lotz, Hiroshi Asahara, Naoki Ishiguro Arthritis Research & Therapy 2013, 15:R28 (13 February 2013) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	Research article Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis Akihiko Hasegawa, Hiroyuki Nakahara, Mitsuo Kinoshita, Hiroshi Asahara, James Koziol, Martin K Lotz Arthritis Research & Therapy 2013, 15:R29 (14 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Clinical characteristics in subjects with NLRP3 V198M diagnosed at a single UK center and a review of the literature Dorota M Rowczenio, Hadija Trojer, Tonia Russell, Anna Baginska, Thirusha Lane, Nicola M Stewart, Julian D Gillmore, Philip N Hawkins, Patricia Woo, Bozena Mikoluc, Helen J Lachmann Arthritis Research & Therapy 2013, 15:R30 (19 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article IL-17-mediated Bcl-2 expression regulates survival of fibroblast-like synoviocytes in rheumatoid arthritis through STAT3 activation Seon-Yeong Lee, Seung-Ki Kwok, Hye-Jin Son, Jun-Geol Ryu, Eun-Kyung Kim, Hye-Jwa Oh, Mi-La Cho, Ji Ju, Sung-Hwan Park, Ho-Youn Kim Arthritis Research & Therapy 2013, 15:R31 (20 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Periodic knee injections of collagen tripeptide delay cartilage degeneration in rabbit experimental osteoarthritis Takuya Naraoka, Yasuyuki Ishibashi, Eiichi Tsuda, Yuji Yamamoto, Tomomi Kusumi, Satoshi Toh Arthritis Research & Therapy 2013, 15:R32 (22 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article The schedule of administration of canakinumab in cryopyrin associated periodic syndrome is driven by the phenotype severity rather than the age Roberta Caorsi, Loredana Lepore, Francesco Zulian, Maria Alessio, Achille Stabile, Antonella Insalaco, Martina Finetti, Antonella Battagliese, Giorgia Martini, Chiara Bibalo, Alberto Martini, Marco Gattorno Arthritis Research & Therapy 2013, 15:R33 (26 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Exercise and obesity in fibromyalgia: beneficial roles of IGF-1 and resistin? Jan L Bjersing, Malin Erlandsson, Maria I Bokarewa, Kaisa Mannerkorpi Arthritis Research & Therapy 2013, 15:R34 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice Olivia Weigert, Caroline von Spee, Reinmar Undeutsch, Lutz Kloke, Jens Y Humrich, Gabriela Riemekasten Arthritis Research & Therapy 2013, 15:R35 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
	Research article Urinary CD8⁺T-cell counts discriminate between active and inactive lupus nephritis Sebastian Dolff, Wayel H Abdulahad, Suzanne Arends, Marcory CRF van Dijk, Pieter C Limburg, Cees GM Kallenberg, Marc Bijl Arthritis Research & Therapy 2013, 15:R36 (27 February 2013) Abstract \| Full text \| PDF \| PubMed

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