Table 1

Proportion of pediatric patients with lupus nephritis-associated ESRD who received renal biopsies and medications prior to ESRD

Renal biopsy

Corticosteroids

HCQ

Immunosuppressants


n (%)

P valuea

n (%)

P valuea

n (%)

P valuea

n (%)

P valuea


Total

254

Sex

Female

182

89 (49)

0.15

167 (92)

0.47

117 (64)

0.38

121 (66)

0.85

Male

72

28 (39)

64 (89)

42 (58)

47 (65)

Race/ethnicity

White

25

14 (56)

0.52

22 (88)

0.19

11 (44)

1 × 106

13 (52)

0.02

Black

155

74 (48)

139 (90)

91 (59)

103 (66)

Hispanic

48

21 (44)

47 (98)

44 (92)

34 (71)

Asian

17

-

16 (94)

-

15 (88)

Native

-

-

-

-

-

SES group

Quartile 1 - lowest

63

37 (59)

0.02b

60 (95)

0.21b

36 (57)

0.33b

42 (67)

0.95b

Quartile 2

63

27 (43)

56 (89)

41 (65)

42 (67)

Quartile 3

63

29 (46)

58 (92)

39 (62)

42 (67)

Quartile 4 - highest

64

23 (36)

56 (88)

43 (67)

42 (66)

Region of residence

Northeast

35

10 (29)

0.09

30 (86)

0.004

22 (63)

0.01

30 (58)

0.53

Midwest

52

26 (50)

43 (83)

23 (44)

23 (66)

South

123

63 (51)

120 (98)

81 (66)

85 (69)

West

44

18 (41)

38 (86)

33 (75)

30 (68)

Residence in health professional shortage area

Not HPSA

13

-

0.78

13 (100)

0.48

-

0.09

11 (85)

0.12

HPSA

240

110 (46)

217 (90)

151 (63)

157 (65)

Pediatric rheumatologist per state

Quartile 1 - lowest

63

38 (60)

0.0002b

59 (94)

0.24b

35 (56)

0.02b

43 (68)

0.50b

Quartile 2

64

34 (53)

62 (97)

37 (58)

46 (72)

Quartile 3

72

30 (42)

63 (88)

46 (64)

42 (58)

Quartile 4 - highest

55

15 (27)

47 (85)

41 (75)

37 (67)


-, cell sizes under 11 have been suppressed in accordance with Centers for Medicare and Medicaid Services policy to protect privacy. aP value for chi-square tests and Fisher's exact tests for small cell counts. bP value for Cochran-Armitage Trend tests.

Hiraki et al. Arthritis Research & Therapy 2012 14(Suppl 3):A58   doi:10.1186/ar3992