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This article is part of the supplement: Proceedings of the 8th Global Arthritis Research Network (GARN) Meeting and 1st Bio-Rheumatology International Congress (BRIC)

Poster presentation

Community-based epidemiological study on hyperuricemia and gout over 5 years in Huang-pu district, Shanghai

Hui Du1*, Shun-Le Chen1, Chun-De Bao1, Xiao-Dong Wang1, Yuan Wang1, Yue-Ying Gu1 and Kusuki Nishioka2

  • * Corresponding author: Hui Du

Author Affiliations

1 Department of Rheumatology, Ren Ji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200001, China

2 Institute of Medical Science, Tokyo Medical University, Tokyo 160-8402, Japan

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Arthritis Research & Therapy 2012, 14(Suppl 1):P26  doi:10.1186/ar3627


The electronic version of this article is the complete one and can be found online at: http://arthritis-research.com/content/14/S1/P26


Published:9 February 2012

© 2012 Du et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Background

A community-based survey on the prevalence of hyperuricemia and associated factors was carried out in 1996 and 2001.

Materials and methods

In the target community in1996, 2037 dwellers (age≥15 years old) were interviewed with relevant questionnaires from house to house. According to even house number, 807 blood samples (age≥ 40 years old) were taken for serum uric acid (SUA) levels measured with the uricase-peroxidase enzymatic method. In 2001, 830 residents ≥ 40 years of age were taken for SUA levels measured with the same enzymatic method. Cholesterol, triglyceride, blood urea nitrogen, glycosylated hemoglobin, ESR, rheumatoid factor etc were measured as possible risk factors to enter the multiple logistic regression analysis on hyperuricemia.

Results

The prevalence of hyperuricemia was 15.1% (51 cases/338, SUA>7 mg/dl) in men, 8.7% in women (41 cases/469, SUA>6 mg/dl) and seven gout male patients were found in 1996. The prevalence of hyperuricemia was 19.5% (52 cases/266, SUA>7 mg/dl) in men, 12.6% (71 cases/564, SUA>6 mg/dl) in women in 2001.The prevalence of gout in 2037 dwellers in Huangpu District was 0.77% in men and 0.34% in both sexes in 1996 [1].

Conclusions

The mean SUA level in each age group in 2001 was higher than that of in 1996(see Table 1). The prevalence of hyperuricemia was increased rapidly (Male: 15.1% in 1996 to 19.5% in 2001; Female: 8.7% in 1996 to 12.6% in 2001 p < 0.05). Azotemia (≥23 vs. <23 mg/dl), hypertriglyceridemia (≥200 vs. <150 mg/dl, 150--200 vs. <150 mg/dl) were the associated risk factors by multiple logistic regression analyzing the independent effect of each variable on hyperuricemia.

Table 1. Comparison of SUA levels in different age group over 5 years

References

  1. Chen S, Du H, Wang Y, Xu L: The epidemiology study of hyperuricemia and gout in a community population of Huangpu District in Shanghai.

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