Table 2 |
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|
Longitudinal regression of joint damage and TNFA -308G > A genotype (n = 208) |
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|
Effect |
Estimate |
Standard error (estimate) |
P-value |
|
|
|||
|
Intercept |
5.8 |
1.18 |
< 0.0001 |
|
Genotype GA+AA |
-5.0 |
1.62 |
0.0020 |
|
Year |
1.6 |
0.38 |
< 0.0001 |
|
Year2 |
-0.13 |
0.020 |
< 0.0001 |
|
Genotype GA+AA × year |
0.17 |
0.34 |
0.61 |
|
|
|||
|
Shown are the variables in the longitudinal regression analysis over 9 years, with joint erosion score as the dependent variable and TNFA -308G > A or TNFA -308G > A × year as primary dependent variables. Year2 allows for a non-linear course of joint progression score over time. The analysis was corrected for gender, and time-averaged 28-joint disease activity score (DAS28), rheumatoid factor and age were not confounders. |
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|
Toonen et al. Arthritis Research & Therapy 2012 14:R264 doi:10.1186/ar4110 |
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