Table 1

Demographics of the inception cohort (n = 208)

GG

GA+AA

Number

(n = 138)

(n = 64 + 6)

P-value

Age, years, mean (SD)

52 (13)

50 (13)

0.21

Female gender, n (%)

89 (64%)

50 (71%)

0.32

RF positivity, n (%)

105 (76%)

55 (79%)

0.69

DAS28, mean (SD)

Baseline

208

5.2 (1.4)

5.3 (1.3)

0.38

3-year average

208

4.0 (1.1)

3.9 (1.0)

0.85

6-year average

159

4.0 (1.0)

3.7 (1.0)

0.10

9-year average

115

4.0 (1.0)

3.7 (1.0)

0.12

Patients with erosions at baseline, n (%)

208

76 (55%)

44 (63%)

0.28

Ratingen score, median (range)

Baseline

208

0 (0-2)

0 (0-2)

0.17

3 years

208

7 (0-15)

4 (0-10)

0.08

6 years

160

12 (2-26)

10 (1-21)

0.18

9 years

116

22 (10-38)

14 (3-24)

0.07

Percentages are expressed in relation to the total number of patients for each genotype group. RF, rheumatoid factor; DAS28, 28-joint disease activity score.

Toonen et al. Arthritis Research & Therapy 2012 14:R264   doi:10.1186/ar4110