Cartilage regeneration culture: IL-6 production. Passage 2 expanded chondrocytes from healthy (H), defect (CD) and osteoarthritic (OA) cartilage were seeded at high density on type II collagen-coated filters and cultured during 28 days. Concentrations of IL-6 in conditioned media of chondrocytes during regeneration on Day 7 is shown; a = P < 0.001.
Tsuchida et al. Arthritis Research & Therapy 2012 14:R262 doi:10.1186/ar4107