Table 7

Serologies of patients with ankylosing spondylitis stratified by fecal calprotectin

AS fCAL-positive versus fCAL-negative (cutoff 50 μg/g)


Median AS fCAL-positive

Median AS fCAL-negative

P value


IgA ASCA (ELISA units)

1.9

0.2

0.05

IgG ASCA (ELISA units)

11.5

6.2

0.003

I2 (ELISA units)

4

6.8

0.36

OmpC (ELISA units)

8.4

6.1

0.34

Cbir1 Fla (ELISA units)

27.2

16.2

0.002

ANCA (ELISA units)

9.2

5

0.06


ANCA, antineutrophil cytoplasmic antibodies; AS, ankylosing spondylitis; ASCA, anti-Saccharomyces cerevisiae antibody; CBir1, anti-flagellin; fCAL, fecal calprotectin; OmpC, anti-Escherichia coli outer membrane porin C.

Matzkies et al. Arthritis Research & Therapy 2012 14:R261   doi:10.1186/ar4106

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