Table 6

Serologies of ankylosing spondylitis patients and healthy controls stratified by fecal calprotectin

Healthy controls (all) compared with AS patients (fCAL cutoff 50 μg/g)


Median HC

Median AS fCAL-negative

P value (HC versus fCAL-negative)

Median AS fCAL-positive

P value (HC versus fCAL-positive)


IgA ASCA (ELISA units)

0.4

0.2

0.478

1.9

0.110

IgG ASCA (ELISA units)

6.7

6.2

0.344

11.5

0.023

I2 (ELISA units)

5.7

6.8

0.394

4

0.703

OmpC (ELISA units)

5.7

6.1

0.904

8.4

0.240

Cbir1 Fla (ELISA units)

15.9

16.2

0.659

27.2

0.003

ANCA (ELISA units)

4.3

5

0.240

9.2

< 0.001


ANCA, antineutrophil cytoplasmic antibodies; AS, ankylosing spondylitis; ASCA, anti-Saccharomyces cerevisiae antibody; CBir1, anti-flagellin; fCAL, fecal calprotectin; HC, healthy controls; OmpC, anti-Escherichia coli outer membrane porin C.

Matzkies et al. Arthritis Research & Therapy 2012 14:R261   doi:10.1186/ar4106

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