Table 2 |
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Regression analysis between general characteristics, disease-related characteristics, classical cardiovascular disease risk factors and the SEVR |
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Primary cohort |
Validation cohort |
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General characteristics |
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Age |
β = 0.02, P = 0.79 |
β = 0.03, P = 0.73 |
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Gender |
0.97 (0.96 to 0.99)* |
0.98 (0.96 to 0.99)* |
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Disease-related characteristics |
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Log disease duration |
β = 0.21, p = 0.01 |
β = 0.12, P = 0.21 |
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RF positivity |
0.90 (0.99 to 1.02) |
n/a |
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Log ESR |
β = -0.20, P = 0.01 |
β= -0.144, P = 0.131 |
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Log CRP |
β = -0.23, P = 0.003 |
β = -0.28, P = 0.002 |
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DAS28 |
β = -0.12, P = 0.09 |
n/a |
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HAQ |
β = -0.11, P = 0.16 |
n/a |
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Classical CVD risk factors |
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Body mass index |
β = - 0.13, P = 0.05 |
β = - 0.19, P = 0.18 |
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Pulse pressure |
β = -0.23, P = 0.004 |
β = - 0.21, P = 0.017 |
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Mean blood pressure |
β = -0.10, P = 0.15 |
β = -0.17, P = 0.05 |
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Heart rate |
β = -0.64, P < 0.001 |
β = -0.76 P < 0.001 |
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Total cholesterol |
β = -0.12, P = 0.09 |
β = -0.14, P = 0.14 |
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TC:HDL ratio |
β = -0.02, P = 0.76 |
β = -0.09, P = 0.35 |
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Triglycerides |
β = -0.01, P = 0.90 |
β = 0.01, P = 0.94 |
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Data presented as β and P values or odds ratio (95% confidence interval). CRP, C reactive protein; CVD, cardiovascular disease; DAS28, Disease Activity Score in 28 joints; ESR, erythrocyte sedimentation rate; HAQ, Health Assessment Questionnaire; HDL, high density lipoprotein; n/a, not available; RF, rheumatoid factor; SEVR, subendocardial viability ratio; TC, total cholesterol. *P < 0.001. Bold data represent statistically significant results. |
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Sandoo et al. Arthritis Research & Therapy 2012 14:R258 doi:10.1186/ar4103 |
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