Table 2 |
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|
Inflammation and osteoblast-associated genes over-expressed in proteoglycan-induced spondylitis (PGISp) spines |
|||
|
Gene |
Fold change PGISp/Control |
P-value |
Gene symbol |
|
|
|||
|
Matrix metallopeptidase 3 |
5.29 |
3.50E-05 |
Mmp3 |
|
Matrix metallopeptidase 13 |
2.26 |
0.0086 |
Mmp13 |
|
Tissue inhibitor of metalloproteinase 1 |
3.48 |
0.0003 |
Timp1 |
|
Interleukin 1, beta |
1.57 |
0.0087 |
Il1b |
|
Interleukin 1 receptor, type II |
1.28 |
0.0000 |
Il1r2 |
|
interleukin 28 receptor alpha |
1.18 |
0.0068 |
Il28ra |
|
Signal transducer and activator of transcription 1 |
1.18 |
0.0150 |
Stat1 |
|
Signal transducer and activator of transcription 3 |
1.21 |
0.0039 |
Stat3 |
|
Bone sialoprotein |
2.62 |
0.0001 |
Ibsp |
|
Collagen Type I |
2.51 |
0.0005 |
Col1a1 |
|
Collagen Type III |
2.42 |
0.0004 |
Col3a1 |
|
Osteocalcin |
1.50 |
0.0297 |
Bglap1 |
|
|
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|
Haynes et al. Arthritis Research & Therapy 2012 14:R253 doi:10.1186/ar4096 |
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