Table 2

Correlations of serum levels for BLyS and APRIL to lupus activity parameters, pathological scores, and renal and systemic involvement at baseline.

BLyS

APRIL


Renal parameters

R_SLEDAI

-0.17

0.22

Serum creatinine

mg/dl

0.06

0.06

Erythrocyturia

cells/high power field

-0.13

0.06

Urine protein

g/day

-0.05

0.44**

Activity score

-0.11

0.34*

Chronicity score

0.25

0.20

Lupus parameters

ANA titer

-0.20

0.02

Anti-dsDNA titer

-0.28

0.23

Complement factor 3

mg/dl

0.46**

-0.44**

Total leukocyte count

cells/mm3

-0.49***

0.26

Polymorph

cells/mm3

-0.40**

0.18

Lymphocyte

cells/mm3

-0.42***

-0.14

Treatment

Prednisolone

mg/day

0.46***

0.25

Mycophenolate

mg/day

0.37**

-0.09


ANA, antinuclear antibody; APRIL, a proliferation-inducing ligand; BlyS, B lymphocyte activation protein; R_SLEDAI, renal Systemic Lupus Erythematous Disease Activity Index. *P < 0.05, **P < 0.01, ***P < 0.001.

Treamtrakanpon et al. Arthritis Research & Therapy 2012 14:R252   doi:10.1186/ar4095

Open Data