Table 1

Characteristics of the patients with Kawasaki disease (KD) and healthy children (control group)

Characteristic

Kawasaki disease

Control

Acute stage

P

Afebrile stage

P

Subacute stage

P


Boys/girls, number

22/18

NS

11/4

Age, months (range)

23.2 (5.1-72.0)

NS

63.7 (2.6-109.0)

Days of fever (range)

6.3 (3.0-15.0)

--

--

Resistin, 102 ng/ml

0.38 (0.25)

0.001

0.24 (0.22) **

0.360

0.14 (0.09) **

0.405

0.19 (0.16)

S100A12, 102 ng/ml

5.33 (3.23)

0.001

4.07 (3.52) *

0.031

2.62 (2.64) **

0.542

2.05 (1.81)

sRAGE, 102 pg/ml

3. 00 (1.91)

0.000

5.75 (2.83) **

0.001

6.83 (3.07) **

0.018

9.04 (5.28)

Resistin × S100A12, 104

2.61 (2.58)

0.000

1.20 (1.19) **

0.122

0.24 (0.23) **

0.877

0.32 (0.26)

Resistin/sRAGE, 102

2.13 (1.89)

0.000

0.39 (0.28) **

0.708

0.21 (0.14) **

0.884

0.26 (0.21)

S100A12/sRAGE, 103

2.61 (2.02)

0.000

0.84 (0.69) **

0.107

0.30 (0.25) **

0.835

0.23 (0.19)

WBCs, 104/ul

1.39 (0.49)

--

1.01 (0.51) **

--

1.01 (0.51) **

--

--

Neutrophils, %

55.6 (18.8)

--

33.2 (17.2) **

--

33.4 (17.6) **

--

--

Lymphocytes, %

32.5 (15.1)

--

50.9 (16.6) **

--

54.3 (16.7) **

--

--

Monocytes, %

7.81 (3.98)

--

11.6 (16.6)

--

8.77 (2.94)

--

--

Platelets, 105/ul

4.23 (1.44)

--

5.68 (2.09) **

--

6.79 (1.87) **▲▲

--

--

CRP, mg/l

75.1 (49.1)

--

25.0 (33.8) **

--

3.25 (4.12) **▲▲

--

--

ESR, mm/h

67.7 (29.7)

--

78.8 (30.4) **

--

59.2 (28.3) ▲▲

--

--


Results are mean (SD) unless stated otherwise. All P-values are for patients versus healthy controls. NS, not significant; sRAGE, soluble receptor for advanced glycation end products; WBCs, white blood cells; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate. *P < 0.05, **P < 0.01 compared with acute stage; P < 0.05, ▲▲P < 0.01 compared with afebrile stage.

Qi et al. Arthritis Research & Therapy 2012 14:R251   doi:10.1186/ar4094

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