Table 5 |
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|
Multivariable-adjusted* predictors of use of opioid pain medications after primary total knee arthroplasty |
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|
Multivariable-adjusted* analysis, 2-year follow-up |
Multivariable-adjusted* analysis, 5-year follow-up |
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|
|
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|
Odds ratio |
(95% CI) |
P-value |
Odds ratio |
(95% CI) |
P-value |
|
|
|
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|
Male gender (reference female) |
0.54 |
(0.32, 0.92) |
0.02a |
0.39 |
(0.18, 0.84) |
0.02a |
|
Age (reference ≤ 60 yrs) |
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|
> 60 to 70 yrs |
0.66 |
(0.36, 1.20) |
0.17 |
0.80 |
(0.38, 1.70) |
0.57 |
|
> 70 to 80 yrs |
0.27 |
(0.13, 0.57) |
0.001a |
0.34 |
(0.14, 0.83) |
0.02a |
|
> 80 yrs |
0.48 |
(0.19, 1.22) |
0.12 |
0.39 |
(0.10, 1.57) |
0.19 |
|
Body mass index (reference < 25 kg/m2) |
||||||
|
25.0 to 29.9 |
1.00 |
(0.46, 2.17) |
1.00 |
0.65 |
(0.24, 1.74) |
0.39 |
|
30.0 to 34.9 |
1.10 |
(0.50, 2.44) |
0.81 |
0.88 |
(0.31, 2.47) |
0.80 |
|
35.0 to 39.9 |
1.25 |
(0.49, 3.22) |
0.64 |
0.86 |
(0.29, 2.58) |
0.79 |
|
≥ 40.0 |
0.54 |
(0.19, 1.59) |
0.27 |
0.40 |
(0.10, 1.64) |
0.20 |
|
Deyo-Charlson index (5-point change) |
1.28 |
(0.70, 2.33) |
0.43 |
1.03 |
(0.48, 2.21) |
0.93 |
|
Depression (reference no depression) |
1.05 |
(0.55, 2.00) |
0.88 |
1.91 |
(0.83, 4.41) |
0.13 |
|
Anxiety (reference no anxiety) |
3.05 |
(1.62, 5.72) |
0.001a |
3.98 |
(1.68, 9.43) |
0.002a |
|
|
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|
*Adjusted for American Society of Anesthesiologists (ASA) score, distance from the medical center, income, operative diagnosis and implant fixation in addition to all the variables in the table; aSignificant odds ratios and P-values; CI, confidence interval. Goodness of fit statistic calculated as quasi likelihood ratio with lower value indicating a better fit: 2 years, 824.3; 5 years, 519.1. |
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|
Singh and Lewallen Arthritis Research & Therapy 2012 14:R248 doi:10.1186/ar4091 |
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