Table 2 |
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|
Semi-quantitative analysis of staining for NFATc1 and ITAM factors within tissue |
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|
Act RA |
Inact RA |
OA |
Norm |
|
|
|
||||
|
NFATc1 |
2.50 ± 0.21 ♦‡◘ (n = 10) |
0.75 ± 0.23 (n = 8) |
0.77 ± 0.24 (n = 9) |
0.28 ± 0.21 (n = 7) |
|
|
||||
|
Cath K |
0.6 ± 0.22 (n = 10) |
1.12 ± 0.35 (n = 8) |
1.33 ± 0.41 (n = 9) |
1.89 ± 0.35 (n = 9) |
|
|
||||
|
OSCAR |
1.44 ± 0.24 (n = 9) |
0.89 ± 0.39 (n = 9) |
0.89 ± 0.26 (n = 9) |
0 ± 0 (n = 8) |
|
|
||||
|
TREM2 |
3.44 ± 0.17♦‡◘ (n = 9) |
2.55 ± 0.34◘ (n = 9) |
2.44 ± 0.24◘ (n = 9) |
1.77 ± 0.22 (n = 9) |
|
|
||||
|
FcRγ |
2.50 ± 0.31 ♦◘ (n = 10) |
0.88 ± 0.40 (n = 8) |
2.22 ± 0.40 ♦◘ (n = 9) |
0.70 ± 0.26 (n = 10) |
|
|
||||
|
DAP12 |
1.70 ± 0.21♦‡◘ (n = 10) |
0.67 ± 0.29 (n = 9) |
0.89 ± 0.11◘ (n = 9) |
0.40 ± 0.22 (n = 10) |
|
|
||||
|
Mean Score ± SEM; ♦ P < 0.05 significantly different from Inactive RA, ‡ P < 0.05 significantly different from OA, ◘ P < 0.05 significantly different from Normal. |
||||
|
Crotti et al. Arthritis Research & Therapy 2012 14:R245 doi:10.1186/ar4088 |
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