Table 2

Semi-quantitative analysis of staining for NFATc1 and ITAM factors within tissue

Act RA

Inact RA

OA

Norm


NFATc1

2.50 ± 0.21 ♦‡◘

(n = 10)

0.75 ± 0.23

(n = 8)

0.77 ± 0.24

(n = 9)

0.28 ± 0.21

(n = 7)


Cath K

0.6 ± 0.22

(n = 10)

1.12 ± 0.35

(n = 8)

1.33 ± 0.41

(n = 9)

1.89 ± 0.35

(n = 9)


OSCAR

1.44 ± 0.24

(n = 9)

0.89 ± 0.39

(n = 9)

0.89 ± 0.26

(n = 9)

0 ± 0

(n = 8)


TREM2

3.44 ± 0.17♦‡◘

(n = 9)

2.55 ± 0.34◘

(n = 9)

2.44 ± 0.24◘

(n = 9)

1.77 ± 0.22

(n = 9)


FcRγ

2.50 ± 0.31 ♦◘

(n = 10)

0.88 ± 0.40

(n = 8)

2.22 ± 0.40 ♦◘

(n = 9)

0.70 ± 0.26

(n = 10)


DAP12

1.70 ± 0.21♦‡◘

(n = 10)

0.67 ± 0.29

(n = 9)

0.89 ± 0.11◘

(n = 9)

0.40 ± 0.22

(n = 10)


Mean Score ± SEM; ♦ P < 0.05 significantly different from Inactive RA, ‡ P < 0.05 significantly different from OA, ◘ P < 0.05 significantly different from Normal.

Crotti et al. Arthritis Research & Therapy 2012 14:R245   doi:10.1186/ar4088

Open Data