The serum progranulin (PGRN) levels in systemic lupus erythematosus (SLE) patients correlate with disease activities. Correlations are shown between the serum PGRN levels and the SLEDAI scores, the titers of (A) anti-dsDNA antibody (anti-dsDNA Ab) (B), the serum levels of C3 (C), C4 (D), and CH50 (E), as measured in 68 patients with SLE. For all comparisons, significant positive or negative correlations were observed.
Tanaka et al. Arthritis Research & Therapy 2012 14:R244 doi:10.1186/ar4087