Table 2 |
||
|
Single-nucleotide polymorphisms used to compute the genetic risk score |
||
|
Chromosome |
Locus name |
SNP markers |
|
|
||
|
1 |
CD2/CD58 |
rs11586238 |
|
|
||
|
1 |
FCGR2A |
rs12746613 |
|
|
||
|
1 |
MMEL1/TNFRSF14 |
rs10910099 |
|
|
||
|
1 |
PTPN22 |
rs2476601 |
|
|
||
|
1 |
PTPRC |
rs10919563 |
|
|
||
|
2 |
AFF3 |
rs10865035 |
|
|
||
|
2 |
CD28 |
rs1980422 |
|
|
||
|
2 |
CTLA4 |
rs3087243 |
|
|
||
|
2 |
REL |
rs13031237 |
|
|
||
|
2 |
STAT4 |
rs7574865 |
|
|
||
|
3 |
DNASE1L3/PXK |
rs13315591 |
|
|
||
|
4 |
IL2/IL21 |
rs6822844 |
|
|
||
|
4 |
RBPJ |
rs874040 |
|
|
||
|
5 |
GIN1/C5orf30 |
rs26232 |
|
|
||
|
6 |
CCR6 |
rs3093023 |
|
|
||
|
6 |
HLA-DRB1 0401 tag |
rs6910071 |
|
|
||
|
6 |
PRDM1 |
rs548234 |
|
|
||
|
6 |
TAGAP |
rs394581 |
|
|
||
|
6 |
TNFAIP3 locus 1 |
rs6920220 |
|
|
||
|
6 |
TNFAIP3 locus 2 |
rs13192841 |
|
|
||
|
6 |
TNFAIP3 locus 3 |
rs5029937 |
|
|
||
|
8 |
BLK |
rs2736340 |
|
|
||
|
9 |
CCL21 |
rs2812378 |
|
|
||
|
9 |
TRAF1/C5 |
rs10760130 |
|
|
||
|
10 |
IL2RA |
rs2104286 |
|
|
||
|
10 |
PRKCQ |
rs4750316 |
|
|
||
|
12 |
KIF5A/PIP4K2C |
rs1678542 |
|
|
||
|
20 |
CD40 |
rs4810485 |
|
|
||
|
22 |
IL2RB |
rs3218258 |
|
|
||
|
The 28 non-HLA independent rheumatoid arthritis confirmed susceptibility single-nucleotide polymorphisms (SNPs) plus the HLA-DRB1*0401 tag from the meta-analysis by Stahl and colleagues [1] or proxies (in italics in the third colomn) used in the present study are shown here. |
||
|
Viatte et al. Arthritis Research & Therapy 2012 14:R239 doi:10.1186/ar4082 |
||
