Figure 5.

Lacrimal gland function. (A) Epidermal growth factor (EGF) concentration measured in tear washings from different strains. NT, not tested. (B through D) Spearman correlations between tear EGF concentrations and muscarinic 3-receptor band densities (B, measured in Western blot; P = 0.001), lacrimal gland (LG) CD8⁺ T (C, P = 0.002), and CD4⁺ T cells (D, P = 0.004). Percentage of CD8 and CD4 infiltration was measured with flow cytometry. R², coefficient of determination.