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Volume 14 Issue 6
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Comment |
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Rheumatology meets radiology in the hot soup of Gutta
Tim L Jansen Arthritis Research & Therapy 2012, 14:126 (19 December 2012)
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Can measuring urinary biomarkers improve the management of lupus nephritis?
Anisur Rahman Arthritis Research & Therapy 2012, 14:127 (19 December 2012)
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Imaging joints for calcium pyrophosphate crystal deposition: a knock to the knees
Robert Terkeltaub Arthritis Research & Therapy 2012, 14:128 (27 December 2012)
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Lupus nephritis - alarmins may sound the alarm?
Tianfu Wu, Chandra Mohan Arthritis Research & Therapy 2012, 14:129 (31 December 2012)
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Review |
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Epigenetic contributions in the development of rheumatoid arthritis
Kerstin Klein, Caroline Ospelt, Steffen Gay Arthritis Research & Therapy 2012, 14:227 (9 November 2012)
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Biologic adjuvants for fracture healing
Mandeep S Virk, Jay R Lieberman Arthritis Research & Therapy 2012, 14:225 (30 November 2012)
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An update on the hyper-IgE syndromes
Patrick FK Yong, Alexandra F Freeman, Karin R Engelhardt, Steven Holland, Jennifer M Puck, Bodo Grimbacher Arthritis Research & Therapy 2012, 14:228 (30 November 2012)
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Inflammatory lesions in the bone marrow of rheumatoid arthritis patients: a morphological perspective
Serena Bugatti, Antonio Manzo, Roberto Caporali, Carlomaurizio Montecucco Arthritis Research & Therapy 2012, 14:229 (27 December 2012)
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T cells in myositis
Vivianne Malmström, Paulius Venalis, Inka Albrecht Arthritis Research & Therapy 2012, 14:230 (28 December 2012)
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Research |
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Deletion of interferon-γ delays onset and severity of dacryoadenitis in CD25KO mice
Flavia SA Pelegrino, Eugene A Volpe, Niral B Gandhi, De-Quan Li, Stephen C Pflugfelder, Cintia S de Paiva Arthritis Research & Therapy 2012, 14:R234 (1 November 2012)
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Y27, a novel derivative of 4-hydroxyquinoline-3-formamide, prevents the development of murine systemic lupus erythematosus-like diseases in MRL/lpr autoimmune mice and BDF1 hybrid mice
Zhi-Yong Xiao, Shao-Hui Chen, Jun-Ping Cheng, Wen-Xia Zhou, Yong-Xiang Zhang, Ri-Fang Yang, Liu-Hong Yun Arthritis Research & Therapy 2012, 14:R235 (1 November 2012)
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Noninvasive optical characterization of muscle blood flow, oxygenation, and metabolism in women with fibromyalgia
Yu Shang, Katelyn Gurley, Brock Symons, Douglas Long, Ratchakrit Srikuea, Leslie J Crofford, Charlotte A Peterson, Guoqiang Yu Arthritis Research & Therapy 2012, 14:R236 (1 November 2012)
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Comparative analysis of collagen type II-specific immune responses during development of collagen-induced arthritis in two B10 mouse strains
Tsvetelina Batsalova, Ingrid Lindh, Johan Bäcklund, Balik Dzhambazov, Rikard Holmdahl Arthritis Research & Therapy 2012, 14:R237 (1 November 2012)
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Systems analysis of primary Sjögren's syndrome pathogenesis in salivary glands identifies shared pathways in human and a mouse model
Steve Horvath, Abu NM Nazmul-Hossain, Rodney PE Pollard, Frans GM Kroese, Arjan Vissink, Cees GM Kallenberg, Fred KL Spijkervet, Hendrika Bootsma, Sara A Michie, Sven U Gorr, Ammon B Peck, Chaochao Cai, Hui Zhou, David TW Wong Arthritis Research & Therapy 2012, 14:R238 (1 November 2012)
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Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease
Sebastien Viatte, Edward Flynn, Mark Lunt, Joanne Barnes, Madeleine Singwe-Ngandeu, Sylvette Bas, Anne Barton, Cem Gabay Arthritis Research & Therapy 2012, 14:R239 (3 November 2012)
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Citrullination of fibronectin modulates synovial fibroblast behavior
Miriam A Shelef, David A Bennin, Deane F Mosher, Anna Huttenlocher Arthritis Research & Therapy 2012, 14:R240 (5 November 2012)
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Editor’s summary
Altered behaviour of synovial fibroblasts on citrullinated fibronectin suggests interaction of synovial fibroblasts with the citrullinated matrix may play an important role in the pathophysiology of rheumatoid arthritis (RA).
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Effect of autologous platelet-rich plasma-releasate on intervertebral disc degeneration in the rabbit anular puncture model: a preclinical study
Shuji Obata, Koji Akeda, Takao Imanishi, Koichi Masuda, Won Bae, Ryo Morimoto, Yumiko Asanuma, Yuichi Kasai, Atsumasa Uchida, Akihiro Sudo Arthritis Research & Therapy 2012, 14:R241 (5 November 2012)
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TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro
Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen, Hui Wang Arthritis Research & Therapy 2012, 14:R242 (7 November 2012)
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Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus
Jack Hutcheson, Kamala Vanarsa, Anna Bashmakov, Simer Grewal, Deena Sajitharan, Betty Y Chang, Joseph J Buggy, Xin J Zhou, Yong Du, Anne B Satterthwaite, Chandra Mohan Arthritis Research & Therapy 2012, 14:R243 (8 November 2012)
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Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity
Atsushi Tanaka, Hiroshi Tsukamoto, Hiroki Mitoma, Chikako Kiyohara, Naoyasu Ueda, Masahiro Ayano, Shun-ichiro Ohta, Yasushi Inoue, Yojirou Arinobu, Hiroaki Niiro, Takahiko Horiuchi, Koichi Akashi Arthritis Research & Therapy 2012, 14:R244 (11 November 2012)
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The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints
Tania N Crotti, Anak ASSK Dharmapatni, Ekram Alias, Andrew CW Zannettino, Malcolm D Smith, David R Haynes Arthritis Research & Therapy 2012, 14:R245 (12 November 2012)
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IL-32 and IL-17 interact and have the potential to aggravate osteoclastogenesis in rheumatoid arthritis
Young-Mee Moon, Bo-Young Yoon, Yang-Mi Her, Hye-Joa Oh, Jae-Seon Lee, Kyoung-Woon Kim, Seon-Yeong Lee, Yun-Ju Woo, Kyung-Su Park, Sung-Hwan Park, Ho-Youn Kim, Mi-La Cho Arthritis Research & Therapy 2012, 14:R246 (13 November 2012)
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Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3
Marije Oosting, Kathrin Buffen, Subbarao RK Malireddi, Patrick Sturm, Ineke Verschueren, Marije I Koenders, Frank L van de Veerdonk, Jos WM van der Meer, Mihai G Netea, Thirumala-Devi Kanneganti, Leo AB Joosten Arthritis Research & Therapy 2012, 14:R247 (13 November 2012)
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Editor’s summary
An early murine Lyme arthritis model using intra-articular injection of live B.burgdorferi demonstrates that induction of Lyme arthritis is strongly dependent on IL-1β production, suggesting IL-1 may be a future therapeutic target.
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Predictors of use of pain medications for persistent knee pain after primary Total Knee Arthroplasty: a cohort study using an institutional joint registry
Jasvinder A Singh, David G Lewallen Arthritis Research & Therapy 2012, 14:R248 (16 November 2012)
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Editor’s summary
Patients that have had primary Total Knee Arthroplasty (TKA) are more likely to continue using pain medication if they are female, of a younger age, or suffering from depression or anxiety.
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Matrix to predict rapid radiographic progression of early rheumatoid arthritis patients from the community treated with methotrexate or leflunomide: results from the ESPOIR cohort
Bruno Fautrel, Benjamin Granger, Bernard Combe, Alain Saraux, Francis Guillemin, Xavier Le Loet Arthritis Research & Therapy 2012, 14:R249 (19 November 2012)
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Polymorphisms in peptidylarginine deiminase associate with rheumatoid arthritis in diverse Asian populations: evidence from MyEIRA study and meta-analysis
Chun Too, Shahnaz Murad, Jasbir Dhaliwal, Per Larsson, Xia Jiang, Bo Ding, Lars Alfredsson, Lars Klareskog, Leonid Padyukov Arthritis Research & Therapy 2012, 14:R250 (19 November 2012)
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Reverse regulation of soluble receptor for advanced glycation end products and proinflammatory factor resistin and S100A12 in Kawasaki disease
Yanqi Qi, Fangqi Gong, Qing Zhang, Chunhong Xie, Wei Wang, Songling Fu Arthritis Research & Therapy 2012, 14:R251 (21 November 2012)
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APRIL, a proliferation-inducing ligand, as a potential marker of lupus nephritis
Worapot Treamtrakanpon, Pornpen Tantivitayakul, Thitima Benjachat, Poorichaya Somparn, Wipawee Kittikowit, Somchai Eiam-ong, Asada Leelahavanichkul, Nattiya Hirankarn, Yingyos Avihingsanon Arthritis Research & Therapy 2012, 14:R252 (21 November 2012)
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Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors
Katelin R Haynes, Allison R Pettit, Ran Duan, Hsu-Wen Tseng, Tibor T Glant, Matthew A Brown, Gethin P Thomas Arthritis Research & Therapy 2012, 14:R253 (22 November 2012)
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Adherence to a treat-to-target strategy in early rheumatoid arthritis: results of the DREAM remission induction cohort
Marloes Vermeer, Hillechiena H Kuper, Hein J Bernelot Moens, Monique Hoekstra, Marcel D Posthumus, Piet LCM van Riel, Mart AFJ van de Laar Arthritis Research & Therapy 2012, 14:R254 (23 November 2012)
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A regulatory effect of IL-21 on T follicular helper-like cell and B cell in rheumatoid arthritis
Rui Liu, Qian Wu, Dinglei Su, Nan Che, Haifeng Chen, Linyu Geng, Jinyun Chen, Wanjun Chen, Xia Li, Lingyun Sun Arthritis Research & Therapy 2012, 14:R255 (23 November 2012)
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Intensity-dependent effect of treadmill running on lubricin metabolism of rat articular cartilage
Guo-Xin Ni, Lei Lei, Yue-Zhu Zhou Arthritis Research & Therapy 2012, 14:R256 (24 November 2012)
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Editor’s summary
High-intensity running in rats lowers lubricin content of joints and increases damage to cartilage while lower intensity running increases lubricin levels and improves joint fitness.
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Association of a BMP5 microsatellite with knee osteoarthritis: case-control study
Cristina Rodriguez-Fontenla, Andrew Carr, Juan J Gomez-Reino, Aspasia Tsezou, John Loughlin, Antonio Gonzalez Arthritis Research & Therapy 2012, 14:R257 (27 November 2012)
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The role of inflammation, the autonomic nervous system and classical cardiovascular disease risk factors on subendocardial viability ratio in patients with RA: a cross-sectional and longitudinal study
Aamer Sandoo, Athanassios D Protogerou, James Hodson, Jacqueline P Smith, Evi Zampeli, Petros P Sfikakis, George D Kitas Arthritis Research & Therapy 2012, 14:R258 (28 November 2012)
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Interleukin-32-induced thymic stromal lymphopoietin plays a critical role in macrophage differentiation through the activation of caspase-1 in vitro
Hyun-Ja Jeong, Sun-Young Nam, Hyun-A Oh, Na-Ra Han, Young-Sick Kim, Phil-Dong Moon, Seung-Youp Shin, Min-Ho Kim, Hyung-Min Kim Arthritis Research & Therapy 2012, 14:R259 (28 November 2012)
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Raised circulating tenascin-C in rheumatoid arthritis
Theresa H Page, Peter J Charles, Anna M Piccinini, Vicky Nicolaidou, Peter C Taylor, Kim S Midwood Arthritis Research & Therapy 2012, 14:R260 (29 November 2012)
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Markers of intestinal inflammation in patients with ankylosing spondylitis: a pilot study
Franziska G Matzkies, Stephan R Targan, Dror Berel, Carol J Landers, John D Reveille, Dermot PB McGovern, Michael H Weisman Arthritis Research & Therapy 2012, 14:R261 (29 November 2012)
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Interleukin-6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model
Anika I Tsuchida, Michiel Beekhuizen, Marijn Rutgers, Gerjo JVM van Osch, Joris EJ Bekkers, Arjan GJ Bot, Bernd Geurts, Wouter JA Dhert, Daniel BF Saris, Laura B Creemers Arthritis Research & Therapy 2012, 14:R262 (3 December 2012)
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Disease activity and cognition in rheumatoid arthritis: an open label pilot study
Graham Raftery, Jiabao He, Ruth Pearce, Daniel Birchall, Julia L Newton, Andrew M Blamire, John D Isaacs Arthritis Research & Therapy 2012, 14:R263 (4 December 2012)
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Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis
Erik JM Toonen, Pilar Barrera, Jaap Fransen, Arjan PM de Brouwer, Agnes M Eijsbouts, Pierre Miossec, Hubert Marotte, Hans Scheffer, Piet LCM van Riel, Barbara Franke, Marieke JH Coenen Arthritis Research & Therapy 2012, 14:R264 (7 December 2012)
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Efficacy and safety of lenalidomide for refractory cutaneous lupus erythematosus
Josefina Cortés-Hernández, Gabriela Ávila, Miquel Vilardell-Tarrés, Josep Ordi-Ros Arthritis Research & Therapy 2012, 14:R265 (7 December 2012)
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Editor’s summary
Lenalidomide, a thalidomide derivative, is effective and safe for the treatment of refractory cutaneous lupus erythematosus in patients recruited to a phase II clinical study.
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Citrullinated fibronectin inhibits apoptosis and promotes the secretion of pro-inflammatory cytokines in fibroblast-like synoviocytes in rheumatoid arthritis
Lieying Fan, Qiang Wang, Rongqing Liu, Ming Zong, Dongyi He, Hui Zhang, Yuanyuan Ding, Jianwei Ma Arthritis Research & Therapy 2012, 14:R266 (10 December 2012)
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The effect of Link N on differentiation of human bone marrow-derived mesenchymal stem cells
John Antoniou, Hong Wang, Abdulrahman M Alaseem, Lisbet Haglund, Peter J Roughley, Fackson Mwale Arthritis Research & Therapy 2012, 14:R267 (10 December 2012)
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Silencing of microRNA-101 prevents IL-1β-induced extracellular matrix degradation in chondrocytes
Linghui Dai, Xin Zhang, Xiaoqing Hu, Chunyan Zhou, Yingfang Ao Arthritis Research & Therapy 2012, 14:R268 (10 December 2012)
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Autoantibody-mediated arthritis in the absence of C3 and activating Fcγ receptors: C5 is activated by the coagulation cascade
Jennifer L Auger, Stefanie Haasken, Bryce A Binstadt Arthritis Research & Therapy 2012, 14:R269 (13 December 2012)
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Suboptimal cardiovascular risk factor identification and management in patients with rheumatoid arthritis: a cohort analysis
Shailey S Desai, James D Myles, Mariana J Kaplan Arthritis Research & Therapy 2012, 14:R270 (13 December 2012)
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Automated interpretation of ANCA patterns - a new approach in the serology of ANCA-associated vasculitis
Ilka Knütter, Rico Hiemann, Therese Brumma, Thomas Büttner, Kai Großmann, Marco Cusini, Francesca Pregnolato, Maria Borghi, Ursula Anderer, Karsten Conrad, Dirk Reinhold, Dirk Roggenbuck, Elena Csernok Arthritis Research & Therapy 2012, 14:R271 (14 December 2012)
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Ghrelin and adipokines as circulating markers of disease activity in patients with Takayasu arteritis
Hatice Yilmaz, Vedat Gerdan, Didem Kozaci, Dilek Solmaz, Servet Akar, Gercek Can, Aytac Gulcu, Yigit Goktay, Ismail Sari, Merih Birlik, Nurullah Akkoc, Fatos Onen Arthritis Research & Therapy 2012, 14:R272 (21 December 2012)
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KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor
Lara Bossini-Castillo, Carmen P Simeon, Lorenzo Beretta, Jasper Broen, Madelon C Vonk, José Callejas, Patricia Carreira, Luis Rodríguez-Rodríguez, Rosa García-Portales, Miguel A González-Gay, Ivan Castellví, María Camps, Carlos Tolosa, Esther Vicente-Rabaneda, María Egurbide, the Spanish Scleroderma Group, Annemie J Schuerwegh, Roger Hesselstrand, Claudio Lunardi, Jacob M van Laar, Paul Shiels, Ariane Herrick, Jane Worthington, Christopher Denton, Timothy RDJ Radstake, Carmen Fonseca, Javier Martin Arthritis Research & Therapy 2012, 14:R273 (27 December 2012)
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