Open Access Highly Accessed Research article

Restoration of regulatory and effector T cell balance and B cell homeostasis in systemic lupus erythematosus patients through vitamin D supplementation

Benjamin Terrier123, Nicolas Derian12, Yoland Schoindre4, Wahiba Chaara125, Guillaume Geri123, Noël Zahr6, Kubéraka Mariampillai7, Michelle Rosenzwajg1235, Wassila Carpentier8, Lucile Musset9, Jean-Charles Piette7, Adrien Six125, David Klatzmann1235, David Saadoun1237, Cacoub Patrice1237 and Nathalie Costedoat-Chalumeau1237*

Author Affiliations

1 UPMC Université Paris 6, UMR 7211, F-75013 Paris, France

2 Centre National de la Recherche Scientifique (CNRS), UMR 7211, Paris, France

3 INSERM, UMRS959; Groupe Hospitalier Pitié-Salpétrière, 47 boulevard de l'Hôpital, 75013 Paris, France

4 Department of Internal Medicine, Hôpital Foch, 40 rue Worth, 92150 Suresnes, France

5 Department of Biotherapy, Groupe Hospitalier Pitié-Salpétrière, 47 boulevard de l'Hôpital, 75013 Paris, France

6 Department of Pharmacology, Groupe Hospitalier Pitié-Salpétrière, 47 boulevard de l'Hôpital, 75013 Paris, France

7 Department of Internal Medicine, Groupe Hospitalier Pitié-Salpétrière, 47 boulevard de l'Hôpital, 75013 Paris, France

8 P3S post-genomic platform, Groupe Hospitalier Pitié-Salpétrière, 47 boulevard de l'Hôpital, 75013 Paris, France

9 Department of Immunology, Groupe Hospitalier Pitié-Salpétrière, 47 boulevard de l'Hôpital, 75013 Paris, France

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Arthritis Research & Therapy 2012, 14:R221  doi:10.1186/ar4060

Published: 17 October 2012

Additional files

Additional file 1:

Microarray gene expression profile analysis. This file contains additional material and a methods section that describes microarray gene expression profile analysis, and Figure S1 that illustrates clustering analysis of significant modulated signatures in patients at month 2 compared to baseline.

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