Table 2

Distribution of different mannose binding lectin (MBL) phenotypes in clinical categories of systemic lupus erythematosus (SLE)

Clinical categories

High MBL

(n = 44)

Intermediate MBL

(n = 13)

Low MBL

(n = 36)

P-value; odds ratio


Nephritis

13 (29)

4 (31)

10 (28)

NS

Nephritis and carditis, or NPSLE, or serositis

16 (36)

5 (38)

4 (11)

0.01; 4.571

0.04; 5.002

AIHA

4 (9)

3 (23)

3 (8)

NS

Carditis

5 (11)

0

1 (3)

NS

NPSLE

14 (31)

4 (31)

8 (22)

NS

Serositis

8 (18)

3 (23)

7 (19)

NS

Musculoskeletal and cutaneous only

2 (5)

3 (23)

11 (31)

0.002; 9.421


1High vs. Low; 2Intermediate vs. Low; data are number (%) of participants. Based on the plasma MBL levels, SLE patients were categorised as high MBL producers (mean 2.04 μg/ml), intermediate MBL producers (mean 1.03 μg/ml), or low MBL producers (mean 0.33 μg/ml). The Fisher exact test was used to compare the distribution of MBL phenotypes in SLE manifestations. AIHA, autoimmune hemolytic anemia; NPSLE, neuropsychiatric systemic lupus erythematosus; NS, not significant.

Panda et al. Arthritis Research & Therapy 2012 14:R218   doi:10.1186/ar4057

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