Table 2 |
|||||
|
Relation of CRP genotypes to baseline CRP levels |
|||||
|
SNP |
HWE (p) |
Genotype |
Geometric mean CRP (mg/L) (SD) |
n |
P value |
|
|
|||||
|
rs1205 |
0.60 |
GG |
32.17 (2.75) |
272 |
Ref. |
|
GA |
31.51 (2.67) |
270 |
0.81 |
||
|
AA |
26.39 (2.70) |
57 |
0.17 |
||
|
rs1800947† |
0.23 |
CC |
31.93 (2.70) |
533 |
Ref. |
|
CG |
26.47 (2.76) |
66 |
0.15 |
||
|
rs3091244_T |
0.33‡ |
XX |
29.09 (2.73) |
278 |
Ref. |
|
XT |
34.40 (2.72) |
261 |
0.05 |
||
|
TT |
28.94 (2.53) |
60 |
0.97 |
||
|
rs3091244_A¶ |
XX |
31.36 (2.70) |
550 |
Ref. |
|
|
XA |
30.32 (2.68) |
33 |
0.85 |
||
|
|
|||||
|
SNP, single-nucleotide polymorphism; HWE, Hardy-Weinberg Expectation; SD, standard copies of T allele. For the A allele of rs3091244: XX, no copies of A allele; XA one copy of A allele; AA two copies of A allele. † No homozygote minor allele observed in this dataset. ‡ rs3091244_T & rs3091244_A SNPs combined to give HWE of rs3091244. ¶ Homozygote minor alleles grouped with heterozygotes. |
|||||
|
Plant et al. Arthritis Research & Therapy 2012 14:R214 doi:10.1186/ar4052 |
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