Table 3

Independent predictors of mortality in CTD-PAH, determined using multivariable proportional hazards regression analysis

Variable

Adjusted HR (95% CI)

P


WHO FC at baseline

3.42 (1.25 to 9.36)

0.04

mRAP at baseline, mmHg

1.13 (1.04 to 1.24)

0.007

Baseline 6MWD*, m

0.64 (0.43 to 0.97)

0.04

Pericardial effusion

3.39 (1.07 to 10.68)

0.04

Warfarin therapy

0.20 (0.05 to 0.78)

0.02

Combination therapy

0.20 (0.05 to 0.83)

0.03


*hazard ratio relates to each 100 metres increase in 6MWD

6MWD, six minute walk distance; 95% CI, 95% confidence interval; HR, hazard ratio; mRAP, mean right atrial pressure; WHO FC, World Health Organization functional class

Ngian et al. Arthritis Research & Therapy 2012 14:R213   doi:10.1186/ar4051

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