Table 5

Regression analysesa of association between tissue abnormalities from CR and/or MRI and physical examination findings

Bony tenderness (presence)

Crepitus (presence)

Bony enlargement (presence)

Palpable warmth (presence)


Conventional radiography

JSWb

MTF

0.90 (0.82)

2.13 (0.15)

2.22 (0.34)

0.44 (0.43)

LTF

0.96 (0.95)

4.24 (0.18)

1.70 (0.50)

n/a

PF

1.80 (00.27)

1.15 (0.82)

3.09 (0.09)

2.72 (0.35)

Osteophytesb

MTF

0.77 (0.59)

1.40 (0.58)

0.78 (0.74)

0.90 (0.93)

LTF

0.85 (0.81)

n/a

1.29 (0.80)

2.33 (0.53)

PF

1.34 (0.58)

1.45 (0.56)

1.89 (0.34)

3.52 (0.23)

Magnetic resonance imaging

Cartilage integrity

MTF

0.89 (0.25)

1.25 (0.05)

1.18 (0.26)

0.92 (0.72)

LTF

0.88 (0.27)

1.61 (0.02)

1.26 (0.15)

0.75 (0.38)

PF

1.03 (0.74)

1.07 (0.49)

0.94 (0.60)

1.30 (0.11)

Osteophytes

MTF

0.92 (0.32)

1.34 (0.02)

1.05 (0.69)

1.24 (0.31)

LTF

1.06 (0.60)

1.57 (0.01)

1.29 (0.08)

1.19 (0.48)

PF

1.09 (0.20)

1.20 (0.04)

0.99 (0.90)

1.30 (0.17)

BML

MTF

0.97 (0.76)

1.16 (0.27)

1.01 (0.94)

1.04 (0.87)

LTF

0.91 (0.53)

1.38 (0.26)

1.45 (0.05)

1.03 (0.95)

PF

0.84 (0.21)

1.73 (0.12)

0.66 (0.28)

1.29 (0.28)

Effusionc

0.75 (0.52)

7.05 (0.01)

1.10 (0.89)

5.93 (0.14)

Synovitisd

0.84 (0.70)

2.14 (0.21)

1.30 (0.70)

n/a


Data presented as odds ratio (P value). Significant associations (P <0.05) in bold. BML, bone marrow lesion; CR, conventional radiography; JSW, joint space width; LTF, lateral tibiofemoral compartment; MRI, magnetic resonance imaging; MTF, medial tibiofemoral compartment; n/a, not applicable because of empty cells in analysis; PF: patellafemoral compartment. aAdjusted for age, gender and duration of knee symptoms. bDefinite/severe abnormality compared with none/mild abnormality (reference group). cMedium/large effusion compared with no/small effusion (reference group). dPresence of synovitis in at least one region compared with absence of synovitis (reference group).

Knoop et al. Arthritis Research & Therapy 2012 14:R212   doi:10.1186/ar4050

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