Table 4

Regression analysesa of association between tissue abnormalities detected by CR and/or MRI and biomechanical factors

Quadriceps strength (Nm/kg)

Hamstrings strength (Nm/kg)

Proprioceptive accuracy (degrees)

Varus-valgus laxity (degrees)


Conventional radiography

JSWb

MTF

-0.12 (0.16)

0.02 (0.84)

-0.03 (0.78)

-0.22 (0.02)

LTF

-0.07 (0.37)

-0.03 (0.71)

-0.08 (0.42)

0.26 (<0.01)

PF

-0.18 (0.03)

0.09 (0.28)

-0.03 (0.80)

-0.14 (0.13)

Osteophyteb

MTF

-0.03 (0.69)

0.04 (0.66)

-0.10 (0.31)

0.07 (0.47)

LTF

-0.06 (0.51)

0.06 (0.46)

-0.05 (0.63)

0.26 (<0.01)

PF

-0.09 (0.30)

0.06 (0.44)

-0.09 (0.38)

-0.08 (0.37)

Magnetic resonance imaging

Cartilage integrity

MTF

-0.15 (0.07)

0.00 (0.97)

0.11 (0.25)

-0.22 (0.02)

LTF

-0.05 (0.55)

0.09 (0.30)

0.05 (0.61)

0.07 (0.44)

PF

-0.17 (0.04)

0.10 (0.24)

-0.02 (0.86)

-0.11 (0.23)

Osteophytes

MTF

-0.05 (0.56)

0.11 (0.18)

0.08 (0.43)

-0.08 (0.36)

LTF

-0.08 (0.33)

0.05 (0.58)

0.02 (0.88)

0.02 (0.87)

PF

-0.12 (0.15)

-0.01 (0.95)

-0.03 (0.77)

-0.17 (0.06)

BML

MTF

0.03 (0.76)

0.12 (0.13)

0.16 (0.11)

-0.06 (0.48)

LTF

-0.05 (0.54)

0.12 (0.13)

-0.05 (0.62)

0.12 (0.18)

PF

0.01 (0.91)

0.16 (0.06)

-0.17 (0.08)

-0.12 (0.19)

Effusionc

-0.16 (0.05)

-0.08 (0.34)

0.11 (0.26)

0.08 (0.40)

Synovitisd

-0.21 (0.01)

-0.11 (0.17)

0.03 (0.76)

-0.02 (0.83)


Data presented as standardized regression coefficient β (P value). Significant associations (P <0.05) in bold. BML, bone marrow lesion; CR, conventional radiography; JSW, joint space width; LTF, lateral tibiofemoral compartment; MRI, magnetic resonance imaging; MTF, medial tibiofemoral compartment; PF: patellafemoral compartment. aAdjusted for age, gender and duration of knee symptoms. bDefinite/severe abnormality compared with none/mild abnormality (reference group). cMedium/large effusion compared with no/small effusion (reference group). dPresence of synovitis in at least one region compared with absence of synovitis (reference group).

Knoop et al. Arthritis Research & Therapy 2012 14:R212   doi:10.1186/ar4050

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