Table 2

Calf muscle blood oxygenation level-dependent (BOLD) key parameters of all eleven patients with systemic sclerosis (SSc) and twelve volunteers

Volunteers

SSc patients

P-value


T2*min (%)

Soleus, mean (SD)

-10.3 (4.0)

-13.4 (6.9)

0.20

Gastrocnemius, mean (SD)

-8.0 (4.6)

-18.0 (9.9)

0.005

Both, mean (SD)

-9.1 (3.5)

-15.0 (7.3)

0.021

T2*max (%)

Soleus, median (IQR)

26.4 (20.0, 30.6)

15.7 (6.5, 21.9)

< 0.007

Gastrocnemius, median (IQR)

17.2 (9.4, 32.0)

4.3 (0.1, 6.4)

0.002

Both, median (IQR)

20.1 (17.0, 29.6)

9.2 (4.4, 17.5)

0.007

TTP (s)

Soleus, median (IQR)

32.0 (30.0, 35.5)

38.0 (34.0, 54.0)

0.037

Gastrocnemius, median (IQR)

34.0 (27.5, 37.3)

42.0 (38.0, 50.0)

0.002

Both, median (IQR)

33.5 (29.5, 36.5)

39.0 (35.0, 56.0)

0.026

DS60 s *10-4 (s-1)

Soleus, mean (SD)

-17.9 (4.9)

-10.3 (5.7)

0.002

Gastrocnemius, mean (SD)

-14.7 (6.1)

-6.6 (7.0)

< 0.001

Both, mean (SD)

-16.5 (4.6)

-7.3 (4.9)

< 0.001

DS120 s *10-4 (s-1)

Soleus, mean (SD)

-14.8 (3.3)

-6.2 (4.4)

< 0.001

Gastrocnemius, mean (SD)

-11.7 (5.6)

-4.5 (4.9)

0.004

Both, mean (SD)

-13.7 (4.1)

-4.6 (3.6)

<0.001

EV (%)

Soleus mean (SD)

-0.3 (3.9)

1.0 (4.4)

0.45

Gastrocnemius, mean (SD)

0.8 ± 3.3

-0.3 (3.4)

0.41

Both, mean (SD)

-0.7 (4.2)

-0.3 (2.7)

0.77


Parameters were obtained for the soleus and gastrocnemius muscle. Normally distributed parameters are provided as means with SD, non-normally distributed parameters are provided as medians with interquartile ranges (IQR). T2*min, ischemic minimum of T2*; T2*max, T2* peak value during reactive hyperemia; TTP, time to peak; DS, declining slope after hyperemia peaking; EV, T2* end value. T2*min, T2*max and EV were calculated relative to baseline. DS60s and DS120s represent T2*declining slopes between T2*max and 60 s or 120 s afterwards.

Partovi et al. Arthritis Research & Therapy 2012 14:R209   doi:10.1186/ar4047

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