Table 2

WOMAC subscales in patients with inflammatory osteoarthritis of the knee who received open-label adalimumab

Baseline

4 weeks

8 weeks

12 weeks

P valuea

22 weeksb


WOMAC pain

60.8 (17.5)

49.6 (21.0)

40.2 (23.4)

36.1 (23.6)

< 0.0001

41.5 (18.9)

WOMAC stiffness

69.7 (16.3)

58.5 (18.3)

44.1 (26.0)

37.0 (25.1)

< 0.0001

48.6 (20.1)

WOMAC function

66.0 (19.4)

53.2 (20.3)

41.1 (25.8)

39.2 (25.1)

< 0.0001

46.6 (21.3)


Mean (standard deviation) for Western Ontario and McMaster University Osteoarthritis Index (WOMAC) subscales over 22 weeks in 20 patients with inflammatory osteoarthritis of the knee who received open-label adalimumab for 12 weeks. aWeek 12 data versus baseline according to paired t test using last-observation-carried-forward data. bWeek 22 data are based on 16 patients who attended for assessment.

Maksymowych et al. Arthritis Research & Therapy 2012 14:R206   doi:10.1186/ar4044

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