Table 2 |
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|
Circulating baseline levels of metalloproteinases (MMPs) in surviving and non-surviving rheumatoid arthritis patients |
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|
Survivors |
Non survivors by major causes of death |
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|
|
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|
All causes |
Circulatory disease |
Neoplastic disease |
Respiratory disease |
||
|
|
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|
Number |
283 |
204 |
94 |
49 |
42 |
|
MMP-1 |
3.35 |
3.60 |
3.42 |
2.52 |
4.93 |
|
MMP-2 |
129.09 |
141.11 |
150.08 |
137.51 |
139.73 |
|
MMP-3 |
23.22 |
27.42 |
25.63 |
27.89 |
27.42 |
|
MMP-8 |
20.03 |
20.50 |
18.67 |
18.55 |
25.16* |
|
MMP-9 |
384.81 |
375.82 |
377.44 |
386.38 |
449.75 |
|
|
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|
Serum levels of MMPs (ng/ml) are medians.*P (adjusted for age, sex and disease duration) = 0.01 (compared with surviving patients). |
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|
Mattey et al. Arthritis Research & Therapy 2012 14:R204 doi:10.1186/ar4042 |
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