Table 1 |
||||||||
|
Patients' characteristics |
||||||||
|
Baseline cytokine secretion |
Stimulation |
|||||||
|
|
||||||||
|
Normal control |
Granulomatosis with polyangiitis |
Normal control |
Granulomatosis with polyangiitis |
|||||
|
(n = 19) |
(n = 20) |
(n = 10) |
(n = 10) |
|||||
|
|
||||||||
|
Age (yrs, mean and range) |
39.50 (18 to 76) |
51.55 (24 to 71) |
43.30 (23 to 56) |
50.80 (24 to 71) |
||||
|
Sex |
11 male, 8 female |
12 male, 8 female |
7 male, 3 female |
7 male, 3 female |
||||
|
First GPA manifestation till study entry (yrs, median and range) |
3.8 (19 to 0) |
3.3 (9 to 0) |
||||||
|
First GPA diagnosis till study entry (yrs, median and range) |
1.6 (19 to 0) |
3.1 (9 to 0) |
||||||
|
|
||||||||
|
Serologic parameters |
||||||||
|
|
||||||||
|
mean value |
SD |
mean value |
SD |
mean value |
SD |
mean value |
SD |
|
|
WBC (cells/nl) |
6.74 |
1.55 |
8.22 |
2.82 |
7.87 |
1.97 |
7.77 |
2.33 |
|
ESR 1st h (mm) |
8.14 |
3.94 |
33.00 |
27.60 |
8.00 |
2.92 |
52.40 |
35.61 |
|
median |
range |
median |
range |
median |
range |
median |
range |
|
|
CRP (mg/dl) |
1.30 |
0.9 to 5.8 |
0.70 |
0 to 8.6 |
1.50 |
1.3 to 3.4 |
0.85 |
0.1 to 8.6 |
|
C-ANCA-titre (1:) |
80 |
0 to 2560 |
640 |
0 to 2560 |
||||
|
P-ANCA-titre (1:) |
0 |
0 to 640 |
0 |
0 to 61 |
||||
|
|
||||||||
|
Wohlers et al. Arthritis Research & Therapy 2012 14:R203 doi:10.1186/ar4041 |
||||||||
