Alefacept treatment does not affect IL-20 expression in PsA synovium. (A) Representative immunohistochemical staining of IL-20 in the synovium of a PsA patient. (B) Quantification of IL-20 expression in PsA synovium. Results are shown as median IOD (integrated optical density)/mm2 × 105 of 11 patients with PsA. (C) Correlation between the expression of IL-20 and the number of CD55+ FLSs in PsA synovium. Original magnification, ×200. Each dot represents the mean of the 18 high-power fields per patient per time point. CRP, C-reactive protein; DAS28, disease activity score; ESR, erythrocyte sedimentation rate; SJC, swollen-joint count; TJC, tender-joint count; VAS, visual analogue scale (100 mm).
Lebre et al. Arthritis Research & Therapy 2012 14:R200 doi:10.1186/ar4038