Table 1

TRAF3IP2 (Act1) gene chromosome 6q21 single-nucleotide polymorphisms associated with psoriatic arthritis

Single-nucleotide polymorphism

Locus

Allele

Risk allele

C6q21 position

Exonic/Intronic

Reference(s)

rs33980500 (p.D10N)

TRAF3IP2

C

T

111913262

Exonic

[1,17]

rs13196377

TRAF3IP2

G

A

112008531

Intronic

[1]

rs13190932 (p.R74W)

TRAF3IP2

G

A

112019763

Exonic

[1]

rs13210247

TRAF3IP2

A

G

112029413

Intronic

[1,17]

Act1, nuclear factor-kappa-B activator 1; TRAF3IP2, tumor necrosis factor receptor-associated factor 3-interacting protein 2.

Doyle et al. Arthritis Research & Therapy 2012 14:226   doi:10.1186/ar4071